Cellular Pathology Flashcards
plasma membrane
phospholipid bilayer with embedded proteins
nucleus
✓chromatin
✓nucleolus
✓transcription of genes
assist proper folding of proteins and transport across organelle membranes
chaperones
degrade both excess proteins and incorrectly folded proteins
proteasomes
lysosomes
✓ enzymatic digestion of material in the cell
cytoskeleton
structure and movement of cells
actin in various forms- cell shape and movement
microfilaments
polymers of tubulin- organelle movement
microtubules
intermediate filaments
cytokeratin
vimentin
desmin
GFAP
neurofilament proteins
metabolism of hydrogen peroxide and fatty acids
enzymes
important enzyme in protecting the cell from oxidative damage
catalase
mitochondria
✓inner and outer membrane, cristae
✓oxidative phosphorylation (main source of ATP)
RER and Golgi
synthesis and packaging of proteins for export
SER
✓lipid biosynthesis
✓detoxification of harmful compounds
✓sequestration of Ca 2+ ions