Invasion and Metastasis

Question 1

are generally noninvasive, usually grow by expansion, are localized, clearly demarcated from the surrounding tissue and are often but not invariably separated from it by capsule or rim of normal connective tissue.

Answer 1

benign neoplasm

Question 2

usually exhibit local invasiveness or infiltration

Answer 2

malignant neoplasm

Question 3

have the potential to spread to distant sites not directly adjacent with the primary mass, in a process called?

Answer 3

metastasis

Question 4

neoplasm that metastasize are unequivocally malignant, and may occur through?

Answer 4

✓ lymphatics
✓ blood vessels
✓ coelomic spaces
✓ epithelial cavities

Question 5

metastasis may do through via;

Answer 5

✓ embolism
✓ vascular invasion
✓ exfoliation and implantation
✓ transplantation

Question 6

produce enzymes that can degrade adjacent tissues

Answer 6

neoplastic cells

Question 7

the enzymes known to produce neoplastic cells

Answer 7

✓ lysosomal hydrolases
✓ collagenase
✓ plasminogen activator

Question 8

for metastasis to be complete, neoplastic cells must be able to complete the following steps;

Answer 8

✓ release from site of origin
✓ transportation
✓ lodgment at distant site
✓ growth and survival at lodgement site