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Step 1 Andre > tumor genes > Flashcards

tumor genes Flashcards

1
Q

BRAF

A

melanoma

  • NRAS-ind and uncontrolled BRAF activation –> increased activation of nuclear DNA replication –> increased cell growth and differentation –> mets
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2
Q

PDGF, EGFR, IGF, TGF

A

glioblastoma

GF’s

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3
Q

BRCA 1 and 2

A

ovarian cancer
breast cancer
prostate cancer

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Step 1 Andre (42 decks)

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