Tuberculosis Drugs Flashcards
1
Q
Administration of all
A
Oral
2
Q
Rifamycin absorption
A
GI
3
Q
Rifamycin excretion
A
GI
4
Q
Rifamycin side effects
A
Orange-red urine
5
Q
Rifamycin toxicity
A
Rifampicin ramps up CYPs
6
Q
Isoniazid absorption
A
Water soluble
7
Q
Isoniazid excretion
A
Urine (post-acetylation)
8
Q
Isoniazid toxicity
A
Rash and fever, jaundice, peripheral neuritis
9
Q
Ethambutol excretion
A
Urine
10
Q
Ethambutol toxicity
A
Diminished visual acuity (EYEthambutol)
11
Q
Pyrazinamide absorption
A
Excellent penetration
12
Q
Pyrazinamide excretion
A
Kidneys
13
Q
Pyrazinamide toxicity
A
Hepatotoxicity, gout