RA Drugs Flashcards

1
Q

Hydroxychloroquine

A

Safe
Takes a long time to work
Side effects=vision loss “the queen can’t see”

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2
Q

Sulfasalazine

A

Prodrug metabolized in large bowel
Dose-related toxicity (standard)
Hypersensitivity–DO NOT rechallenge

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3
Q

Methotrexate

A

Dominant DMARD

Targets fast-growing cells

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4
Q

Leflunomide

A

Inhibits DHODH

Lesser player in RA

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5
Q

Soluble receptor antagonist

A

Etanercept

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6
Q

Chimeric anti-TNF

A

Infliximab

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7
Q

Human anti-TNF

A

Adalimumab

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8
Q

Anti-IL6

A

Tocilizumab

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9
Q

T cell costimulation blockade

A

Abatacept

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10
Q

B cell depletion

A

Rituximab

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