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Pharmacology > Immunosuppresant Drugs > Flashcards

Immunosuppresant Drugs Flashcards

1
Q

Anti-CD3 antibody

A

Muronomab

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2
Q

Anti-CD52 antibody

A

Alemtuzumab

most potent immunosuppressant

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3
Q

Anti-CD25 antibody

A

Daclizumab/Basiliximab

Non-depleting (IL2R)

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4
Q

Calcineurin inhibitor that binds to cyclophilin

A

Cyclosporine

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5
Q

Calcineurin inhibitor that binds to FKBP12

A

Tacrolimus

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6
Q

Cyclosporine toxicity

A

Nephrotoxicity, neurotoxicity, hirsutism, gum hyperplasia

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7
Q

Tacrolimus toxicity

A

New onset diabetes

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8
Q

mTOR inhibitor

A

Sirolimus

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9
Q

mTOR side effects

A

Impaired wound healing

Interstitial lung disease

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10
Q

Cell cycle inhibitor

A

Azathioprine

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11
Q

Mycophenolate dose-limiting toxicity

A

Diarrhea

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Pharmacology (52 decks)

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