Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Conjugation reactions > Flashcards

Conjugation reactions Flashcards

1
Q

Glucuronidation

A

Glucuronyl transferases
UGT1A1 in adults
UGT2B4 in fetuses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sulfate conjugation

A

Sulfotransferases

Saturable due to PAPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Acetylation

A

NAT-1 and NAT-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Slow acetylation

A

Isoniazid induced neurotoxicity
Drug-induced lupus
Arylamine-induced bladder cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fast acetylation

A

Isoniazid induced hepatitis

Colorectal cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glutathione conjugation

A

Glutathione S transferase

Protects body from reactive chemicals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

GSTM null links

A 
Pituitary adenoma
Head and neck cancer
Malignant melanoma
Colorectal cancer
Bladder cancer
Lung cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Methylation

A

Methyltransferases
SAM
Products are more lipid soluble than substrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Amino acid conjugation

A

Usually as glycine conjugates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharmacology (52 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions