Small molecule inhibitors Flashcards

1
Q

Mutant B-Raf kinase inhibitor (melanoma)

A

Vemurafenib, dabrafenib

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2
Q

MEK1, MEK2 inhibitor (downstream of BRAF–>melanoma)

A

Trametenib

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3
Q

BCR-ABL inhibitor

A

Imatinib

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4
Q

EGFR antibody

A

Panitumumab

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5
Q

HER2 antibody

A

Trastuzumab

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6
Q

CD20 antibody

A

Rituximab

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7
Q

VEGF antibody

A

Bevacizumab

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8
Q

VEGFr inhibitor

A

Pazopanib

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