GI Pharm Flashcards
Benign ulcers
Normal acid production, weak mucosal barrier
Malignant ulcers
Increased acid production, normal mucosal barrier
H2 receptor blockers
-tidine
Cimetidine, famotidine, ranitidine, nizatidine
PPIs
-prazoles
Omeprazole, esomeprazole, rabeprazole, lansoprazole, pantoprazole
Prostaglandin
Misoprostol
Prostaglandin MOA
Maintains mucosal barrier (via COX pathway)
Prostaglandin use
PUD and GERD caused by NSAID injury
Anticholinergic
Pirenzepine
Mucosal protective agents
Sucralfate and chelated bismuth
Triple therapy
PPI, moderate antibiotic, strong antibiotic
Quadruple therapy
PPI, moderate antibiotic, strong antibiotic, chelated bismuth
Treatment for mild Crohn’s
-salazines
Treatment for moderate Crohn’s
Prednisolone
Treatment for active and chronic Crohn’s
Thiopurines, MTX
Laxative MOA
Increase diameter of intestinal lumen