Alkylating agents Flashcards
1
Q
MOA
A
Cause DNA cross-linking–>prevent replication
2
Q
Intrinsic resistance
A
p53 mutation
3
Q
Nitrogen mustards
A
Cyclophosphamide
Melphalan
4
Q
Nitrosureas
A
Carmustine, lomustine
Streptozotocin/Streptozocin
5
Q
Hydrazines
A
Procarbazine
Dacarbazine
6
Q
Platinums
A
Cisplatin
Carboplatin