Tuberculosis: Drug Therapy

Question 1

What is the standard treatment regime for active TB?

Answer 1

4 for 2, 2 for 4. RIPE

• Rifampicin
• Isoniazid
• Pyrazinamide
• Ethambutol

THEN for 4 months.

• Rifampicin
• Isoniazid.

Question 2

What is the treatment for latent TB?

Answer 2

Isoniazid for 6 months.

Question 3

What is the treatment for meningeal TB?

Answer 3

• Prolonged treatment for 12 months.
• Addition of steroids.

Question 4

What is a Directly Observed Therapy regime and who is it used for?

Answer 4

3 time weekly dosing.

Used for:

• Homeless
• Poor concordance
• All prisoners with latent or active TB.