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Pharmacology > Interferon > Flashcards

Interferon Flashcards

1
Q

What are interferons?

A

They are cytokines released by the body in response to viral infections and neoplasia.

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2
Q

Interferons are classified according to their cellular origin and the type of receptor they bind to.

What receptor does IFN-alpha and IFN-beta bind to?

What receptor does IFN-gamma bind to?

A

IFN-alpha and IFN-beta bind to type 1 receptors.

IFN-gamma binds to type 2 receptors.

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3
Q

What cells produce IFN-alpha?

A

Leucocytes

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4
Q

What conditions can IFN-apha treat?

A

Hepatitis B & C

Kaposi’s sarcoma

Metastatic renal cell cancer

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5
Q

What are the adverse effects of IFN-alpha?

A

Flu-like symptoms and depression

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6
Q

What cells produce IFN-beta?

A

Fibroblasts

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7
Q

What is IFN-beta used to treat?

A

Relapsing-remitting MS

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8
Q

What cells produce IFN-gamma?

A

T Lymphocytes and NK cells

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9
Q

What is IFN-gamma used to treat?

A
  • Chronic granulomatous disease
  • Osteoporosis
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Pharmacology (96 decks)

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