Quinolones Flashcards
1
Q
Name some types of quinolone.
A
- Ciprofloxacin
- Levofloxacin
2
Q
What are their mechanism of action?
A
They inhibit topoisomerase 2 (DNA gyrase) and topoisomerase IV.
3
Q
What are some side effects of quinolones?
A
- Lower seizure threshold in epileptics.
- Tendon damage (including rupture)
- Cartilage damage.
4
Q
Should quinolones be given to children?
A
No - due to cartilage damage.
