Co-cyprindiol (Dianette)

Question 1

What 2 conditions can co-cyprindiol(Dianette) be used for?

Answer 1

• Severe acne in women refractory to prolonged oral antibacterial therapy
• Moderately severe hirsutism

Question 2

A women comes in to see you with severe acne after taking antibiotics. You decide to give her Dianette. What would be your advise about Dianette?

Answer 2

The Medicines and Healthcare Products Regulatory Agency (MHRA) advise that due to the increased risk of venous thromboembolism with co-cyprindiol (Dianette), it should be discontinued 3-4 cycles after acne has cleared, and should not be used just for contraception.

Question 3

How does Dianette compare with other COCPs for causing VTEs?

Answer 3

Interestingly, the increased risk appears similar to COCPs that contain desogestrel, gestodene or drospirenone.

COCPs containing levonorgestrel have less chance of causing VTEs.

Question 4

Should a COCP be prescribed on top of Dianette treatment?

Answer 4

No.