Sulfonylureas Flashcards
1
Q
How do sulfonylureas work?
A
They increase insulin secretion from Beta Cells.
(Therefore will not work in T1DM)
2
Q
What are 2 common adverse effects of sulfonylureas?
A
- Hypoglycaemic episodes (more common in long acting preparations like chloropamide)
- Weight gain.
3
Q
In what condition should sulfonylureas be avoided?
A
- Breast feeding
- Pregnancy
4
Q
What are some rare adverse effects?
A
- SIADH
- Bone marrow suppression
- Liver damage (cholestatic)
- Photosensitivity
- Peripheral neuropathy
