Treatment Seizures Flashcards
phenytoin is the 1st drug to suppress ____ w/o depressing entire ____
seizures
CNS
what is the biggest side effect of phenytoin
ginigival hyperplasia
phenytoin decreases effects of what 3 drugs
oral contraceptives
warfarin
glucocoticoids
the dose is highly ___ with phenytoin
individualized
admin phenytoin with what
food
what are the 3 older AED drugs
carbamazepine
valproic acid
phenobarbital
what is carbamazepine used to treat (2)
bipolar disorder
trigeminal neuralgia
what is an adverse effect of of carbamazepine
bone marrow suppression
valproic acid is the 1st line drug for all ____ & _____ seizures
partial
generalized
valproic acid is also used to treat what 2 disorders
bipolar
migraine prevention
what are the adverse affects for valproic acid
hepatotoxicity
pancreatitis
phenobarbital can decrease the effects of what 2 drugs
warfarin
birth control
what are the adverse effects of phenobarbital (3)
drowsiness
interferes w/ metabolism of Vit D & K
what are the 6 newer AEDs
oxcarbazepine
lamotrigine
gabapentin
pregabalin
levetiracetam
topiramate
what is oxcarbazepine used to manage
partial seizures
what are the adverse effects of oxcarbazepine (2)
dizziness
drowsiness
lamotrigine is a broad spectrum drug for ___ ___
antiseizure activity
what other disorder can lamotrigine treat
bipolar disorder
what effects can lamotrigine cause (2)
life-threatening rash
risk for suicide
gabapentin is used for adjunct therapy for ___ seizures
partial
what are common side effects of gabapentin (6)
somnolence
dizziness
ataxia
fatigue
nystagmus
peripheral edema
pregabalin is used for adjunct therapy for ___ seizures
partial
levetiracetam does not interact with other ____
AEDs
toprimate is a broad-spectrum ____
antiseizure drug
what is the 1st line drug we use for acute seizures & status epilepticus
lorazepam
how long do lorazepam effects last
up to 72 hrs
diazepam is a short duration drug and must be admined ___
repeatedly
how much diazepam is admined every 5 to 10 mins
5mg/min
do not exceed ___mg with diazepam
30
anitseizure drugs should not be ____ abruptly as they can cause more ____
stopped
seizures
what type of seizure can we do neurosurgery on and has the best success rate
focal
what procedure can we do when meds no longer work for generalized seizures
vagal nerve stimulation
