Treatment Seizures Flashcards

1
Q

phenytoin is the 1st drug to suppress ____ w/o depressing entire ____

A

seizures
CNS

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2
Q

what is the biggest side effect of phenytoin

A

ginigival hyperplasia

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3
Q

phenytoin decreases effects of what 3 drugs

A

oral contraceptives
warfarin
glucocoticoids

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4
Q

the dose is highly ___ with phenytoin

A

individualized

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5
Q

admin phenytoin with what

A

food

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6
Q

what are the 3 older AED drugs

A

carbamazepine
valproic acid
phenobarbital

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7
Q

what is carbamazepine used to treat (2)

A

bipolar disorder
trigeminal neuralgia

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8
Q

what is an adverse effect of of carbamazepine

A

bone marrow suppression

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9
Q

valproic acid is the 1st line drug for all ____ & _____ seizures

A

partial
generalized

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10
Q

valproic acid is also used to treat what 2 disorders

A

bipolar
migraine prevention

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11
Q

what are the adverse affects for valproic acid

A

hepatotoxicity
pancreatitis

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12
Q

phenobarbital can decrease the effects of what 2 drugs

A

warfarin
birth control

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13
Q

what are the adverse effects of phenobarbital (3)

A

drowsiness
interferes w/ metabolism of Vit D & K

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14
Q

what are the 6 newer AEDs

A

oxcarbazepine
lamotrigine
gabapentin
pregabalin
levetiracetam
topiramate

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15
Q

what is oxcarbazepine used to manage

A

partial seizures

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16
Q

what are the adverse effects of oxcarbazepine (2)

A

dizziness
drowsiness

17
Q

lamotrigine is a broad spectrum drug for ___ ___

A

antiseizure activity

18
Q

what other disorder can lamotrigine treat

A

bipolar disorder

19
Q

what effects can lamotrigine cause (2)

A

life-threatening rash
risk for suicide

20
Q

gabapentin is used for adjunct therapy for ___ seizures

A

partial

21
Q

what are common side effects of gabapentin (6)

A

somnolence
dizziness
ataxia
fatigue
nystagmus
peripheral edema

22
Q

pregabalin is used for adjunct therapy for ___ seizures

A

partial

23
Q

levetiracetam does not interact with other ____

A

AEDs

24
Q

toprimate is a broad-spectrum ____

A

antiseizure drug

25
Q

what is the 1st line drug we use for acute seizures & status epilepticus

A

lorazepam

26
Q

how long do lorazepam effects last

A

up to 72 hrs

27
Q

diazepam is a short duration drug and must be admined ___

A

repeatedly

28
Q

how much diazepam is admined every 5 to 10 mins

A

5mg/min

29
Q

do not exceed ___mg with diazepam

A

30

30
Q

anitseizure drugs should not be ____ abruptly as they can cause more ____

A

stopped
seizures

31
Q

what type of seizure can we do neurosurgery on and has the best success rate

A

focal

32
Q

what procedure can we do when meds no longer work for generalized seizures

A

vagal nerve stimulation