Treatment Seizures Flashcards

1
Q

phenytoin is the 1st drug to suppress ____ w/o depressing entire ____

A

seizures
CNS

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2
Q

what is the biggest side effect of phenytoin

A

ginigival hyperplasia

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3
Q

phenytoin decreases effects of what 3 drugs

A

oral contraceptives
warfarin
glucocoticoids

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4
Q

the dose is highly ___ with phenytoin

A

individualized

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5
Q

admin phenytoin with what

A

food

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6
Q

what are the 3 older AED drugs

A

carbamazepine
valproic acid
phenobarbital

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7
Q

what is carbamazepine used to treat (2)

A

bipolar disorder
trigeminal neuralgia

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8
Q

what is an adverse effect of of carbamazepine

A

bone marrow suppression

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9
Q

valproic acid is the 1st line drug for all ____ & _____ seizures

A

partial
generalized

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10
Q

valproic acid is also used to treat what 2 disorders

A

bipolar
migraine prevention

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11
Q

what are the adverse affects for valproic acid

A

hepatotoxicity
pancreatitis

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12
Q

phenobarbital can decrease the effects of what 2 drugs

A

warfarin
birth control

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13
Q

what are the adverse effects of phenobarbital (3)

A

drowsiness
interferes w/ metabolism of Vit D & K

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14
Q

what are the 6 newer AEDs

A

oxcarbazepine
lamotrigine
gabapentin
pregabalin
levetiracetam
topiramate

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15
Q

what is oxcarbazepine used to manage

A

partial seizures

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16
Q

what are the adverse effects of oxcarbazepine (2)

A

dizziness
drowsiness

17
Q

lamotrigine is a broad spectrum drug for ___ ___

A

antiseizure activity

18
Q

what other disorder can lamotrigine treat

A

bipolar disorder

19
Q

what effects can lamotrigine cause (2)

A

life-threatening rash
risk for suicide

20
Q

gabapentin is used for adjunct therapy for ___ seizures

21
Q

what are common side effects of gabapentin (6)

A

somnolence
dizziness
ataxia
fatigue
nystagmus
peripheral edema

22
Q

pregabalin is used for adjunct therapy for ___ seizures

23
Q

levetiracetam does not interact with other ____

24
Q

toprimate is a broad-spectrum ____

A

antiseizure drug

25
what is the 1st line drug we use for acute seizures & status epilepticus
lorazepam
26
how long do lorazepam effects last
up to 72 hrs
27
diazepam is a short duration drug and must be admined ___
repeatedly
28
how much diazepam is admined every 5 to 10 mins
5mg/min
29
do not exceed ___mg with diazepam
30
30
anitseizure drugs should not be ____ abruptly as they can cause more ____
stopped seizures
31
what type of seizure can we do neurosurgery on and has the best success rate
focal
32
what procedure can we do when meds no longer work for generalized seizures
vagal nerve stimulation