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IM 4 > PD Drugs > Flashcards

PD Drugs Flashcards

1
Q

drugs are given to improve pt’s ability to do ____

A

ADL’s

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2
Q

drugs are prescribed by they extent of how the disease affects the pt’s ___ & ____’s

A

work
ADL’s

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3
Q

what is the most common pd dug

A

levodopa

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4
Q

levodopa is highly effective but____ over time

A

diminishes

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5
Q

what delays levodopa absorption

A

food

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6
Q

what foods can reduce levodopa’s therapeutic effects

A

high protein foods

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7
Q

what are adverse effects of levodopa/carbidopa (8)

A

N/V
dyskinesias
postural hypotension
dysrhythmias
psychosis
impulse control
darkened sweat & urine
loss of effect

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8
Q

what is the 1st drug of choice for mild to moderate symps

A

dopemine agonists

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9
Q

what med is a dopamine agonist

A

pramipexole

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10
Q

pramipexole is used ____ in early PD

A

alone

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11
Q

pramipexole is used with levodopa in _____ PD

A

advanced

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12
Q

what are adverse effects of pramipexole when used by itself (8)

A

SLEEP ATTACKS***
nausea
dizziness
daytime somnolence
insomnia
constipation
weakness
hallucinations

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13
Q

when levodopa & pramipexole are used in combination what are the adverse effects (3)

A

orthostatic hypotension
dyskinesia
increased hallucinations

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14
Q

what two meds are anticholinergics

A

trihexiphenidyl
benztropine

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15
Q

what are adverse effects of anticholinergics (8)

A

dry mouth
urinary retention
tachycardia
blurred vision
constipation
photophobia
confusion
hallucinations

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16
Q

COMT inhibitors help with the metabolism of _____ in the periphery

A

levodopa

17
Q

what are the two COMT inhibitors available

A

entacapone
tolcapone

18
Q

what are the adverse effects of entacapone (7)

A

dyskinesia
orthostatic hypotension
N/V/D
hallucinations
sleep disturbances
impulse control disorders
yellow-orange discoloration of urine

19
Q

what are adverse effects of tolcapone (7)

A

liver failure
dyskinesia
orthostatoc hypotension
hallucinations
sleep disturbances
yellow-orange urine \

20
Q

MAOB-B Inhibitors are considered ____ drugs for PD

A

first-line

21
Q

what are the two MAO-B inhibitors

A

selegiline
rasagiline

22
Q

selegiline can be used ____ or w/ ____

A

alone
levodopa

23
Q

what are the adverse effects of selegiline (6)

A

insomnia
dry mouth
orthostatic hypotension
dizziness
hypertensive crisis
GI symps

24
Q

rasagiline can be used ____ or w/ _____

A

alone
levodopa

25
Q

what are the adverse effects of rasagiline (4)

A

insomnia
orthostatic hypotension
irritation of buccal mucosa
hypertension crisis

IM 4 (62 decks)

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