TREATMENT OF COUGH Flashcards

1
Q

What is meant by cough?

A

A proctective reflex that clears the respiratory tract of accumulated secretion, exudate or foreign bodies. It involves the initial bronchospasms and the closing of epiglottis after which air is forced outside with the trendemous power.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

where is the cough centre?

A

Medulla oblongata

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Underlying causes of cough

A

TB
Foreign bodies in the airway
* Cystic fibrosis
* Immune deficiencies should be ruled out.
* Nocturnal cough = asthma or early congestive heart failure
* Smoking
* Side effects of drugs such as ACE inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the dry cough?

A

cough characterized by no mucus and occur persistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

treatment of dry cough

A

Antitussive=cough suppresants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is wet cough?

A

Mucus-white(viral)
Yellow-green- bacterial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

treatmnet of wet cough

A

expectorant or mucolytic plus adequate hydration to reduce viscosity of the mucus
Antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is mild cough?

A

irritating, no bronchospasm, no bacterial infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

treatment of mild cough

A

honey and lemon
Simple linctus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Evidence for effectiveness of cough preparations

A

Evidence of the efficacy of cough preparations is limited
* Seldom necessary to suppress a cough (might be beneficial in nonproductive
coughs due to fibrosing alveolitis, lung cancer / other
terminal diseases)
* Cysteine-based mucolytic preparations reduce frequency of
exacerbations of COPD
* No good evidence for efficacy of expectorants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what causes acute cough in children

A

Viral respiratory tract infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the treatment of allergic cough and allergic rhinitis in children

A

Antihistamines, plus topical nasal steriods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

types of cough in children that excludes asthma and other underlying conditions

A

chronic cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

For dry cough
* Treatment for
unproductive persistent
cough, which exhausts
the patient.
list medicines

A

Codiene phosphate
Dihydrocodiene
Methadone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

for dry cough
NOT for productive
cough, withholds the
mucus, NOT for bacterial
infections.
List medicines

A

Noscapine
Pholcodine (+Antihistamine)
Dextromethorphan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Opiods related side effects of:
1. Dihydrocodeine
2. codeine phosphate
3. Methodone

A
  1. Suppress cough centre in medulla
  2. Side effect and abuse potential-limit use
  3. C/I: not<2yrs
17
Q

Non-opiods related side effects of:
1. Noscapine

A

suppress cough centre but no anagelsic, euphoric and constipating effects

18
Q

Cough suppresants side effects

A

Adverse effects
* Dizziness, drowsiness, sedation: Avoid alcohol, CNS depressants
* Headaches
* Confusion, excitement (children ++)
* Epigastric discomfort, N, V
* Constipation + biliary colic (opioids)
* O/Dose: Respiratory depression
* Abuse & Addiction: with Codeine & Antihistamine
* C/I: Asthmatic patients, chronic bronchitis

19
Q

Clinical indication of Expectorants

A

Facilitate coughing up mucus and other materials from the lungs
Used for patients with thick, tenacious respiratory secretion, dry non productive coughing, sinusitis to increases airway hydration

20
Q

MOA of exepectorant

A

stimulates bronchial secretion, thinning of mucus for easy removal

21
Q

The use mucolytic

A

use to dissolve thick mucus and usually used to relieve rspiratory difficulties

22
Q

MOA of mucolytic

A

Liquifies mucus by dissolving the mucopolysaccharides (long chain
sugar molecules found in mucus & fluid in joints), reducing its viscosity,
thereby enabling pt. to cough up mucus more easily.

23
Q

examples of mucolytic

A

Bromhexine (Bisolvon®) (+ bronchodilator), Carbocisteine
(Mucospect®) , N-acetylcysteine (Salmucol®)

24
Q

Adverse effects of mucolytic

A

Adverse effects:
* Epigastric discomfort, N, V
* Tinnitus, headache
* Fever, skin rash, urticaria
* Bronchospasm

25
Q

which drug is used as antidote in paracetamol poisoning

A

N-acetycycsteine

26
Q

precautions for cough medication

A
  • Cough suppressants C/I: Asthma patients & Chronic bronchitis
  • Diabetic patients: Pholcodine, Noscapine, Bromhexine +
    bronchodilator
  • Combining Cough suppressant + Expectorant = No justification!
  • Dryness & irritation of throat:
  • Gargle with salt water i.e.
  • 2.5g salt in 250ml water