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PHARMACOLOGY TERM 2 > Introduction to drugs affecting the cardiovascular system 1 > Flashcards

Introduction to drugs affecting the cardiovascular system 1 Flashcards

1
Q

List the cardiovascular diseases
affecting the heart and blood vessels

A
  1. Hypertension
  2. Atherosclerosis
  3. Ischaemic heart disease
  4. Heart failure
  5. Arrythmias
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2
Q

The most prominent risk factor contributing to the prevalence of cardiovascular disease

A

Hypertension

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3
Q

List the 7 cardiovascular drug classification: SAMF

A
  • Cardiac therapy
  • Antihypertensives
  • Diuretics
  • Beta-blocking agents
  • Calcium-channel blockers
  • Agents acting on renin-angiotensin system
  • Serum lipid modifying agents
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4
Q

For cardiac therapy list drugs classes acting on the heart

A

Acting on the heart
* Cardiac glycosides
* Antiarrhythmics
* Cardiac stimulants
* Vasodilators (cardiac disease)
* Other

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5
Q

List the non selective (b1 and b1)

A

Propranolol
Sotalol
Timolol

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6
Q

The non selective beta blocking are contra-indicated for which respiratory condition

A

Asthma

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7
Q

List the drugs for B1 selective

A

Atenolol
Bisoprolol
Esmolol
Metoprolol
Nebivolol

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8
Q

what are the comments about B1 selective blocking agents

A

Cardio-selective
preferred in angina

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9
Q

List the drugs that are vasodilatory non-B1 selective

A

Carvedilol (+a1-blocker)
Labetalol (+NO vasodilatory effect)

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10
Q

The Vasodilatory non B1 selective is preferred in which condition

A

Preferred in CCF

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11
Q

List the 5 indications for beta-blocking agents

A

Angina pectoris (β1-selective)
Acute coronary syndrome / acute MI
Arrhythmias
Congestive cardiac failure (Vasodilatory non-β1-selective)
(Hypertension (β1-selective) 5th line agent)

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12
Q

List the other indication (Non-selective agents)
4 marks

A

Other indications (Non-selective agents)
* Essential tremor
* Symptomatic anxiety
* Adjunct in thyrotoxicosis
* Migraine prophylaxis

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13
Q

List the drugs that are lipid soluble

A

Propranolol
Metoprolol
Labetalol

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14
Q

List drugs that are least lipid soluble

A

Atenolol, sotalol

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15
Q

The least lipid soluble drugs are having fewer side effect to which system

A

CNS

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16
Q

List the 6 beta blocking agents: side effects

A

Bradycardia
Bronchospasm
Masking hypoglycaemia
Fatigue
Cold extremities
Cholesterol dysregulation

17
Q

CNS effects that are caused by lipid soluble

A

Insomnia and depression

18
Q

The long terms studies in hypertension, the uses of which drugs that causes MD2 and less protection from stroke

A

Atenolol and thiazide diuretics

19
Q

The use atenolol with thiazide diuretics suggest increased risk of what?

A

Type 2 DM
Less proctection from stroke

20
Q

Contra-indications/caution of beta blocking agents

A

Asthma and COPD
Heart block
DM
Depression (non-selective)

PHARMACOLOGY TERM 2 (45 decks)

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