transfusion reaction III Flashcards
what are the risk in iron overload
a. thalassemia
b. patient depedent in transfusion
c. hemoglobinopaties
d. sickke cell anema
AOTA
what DHTR has a multi organ failure
a. PTP
b. iron overload
c. ttd
d. TACO
Iron overload / Transfusioninduced Hemosiderosis
delayed, nonimmune complication of transfusion, presenting with multiorgan (i.e., liver, heart, endocrine organs) damage
Signs and Symptoms: Muscle weakness, weight loss, mild jaundice, fatigue, cardiac arrhythmias, mild diabetes, and multi-organ failure
first retrovirus to be associated with a human disease
a. HBV DNA
B. HBIG
C. HTLV -1
D. CMV
HTLV-I was the first retrovirus to be associated with a human disease.
That association was with adult T-cell lymphoma/ leukemia (ATL), a highly aggressive, mature T-cell non- Hodgkin’s lymphoma with a leukemic phase
capable of crossing the blood-brain barrier
a. HBV DNA
B. WNV
C. HTLV -1
D. CMV
West nile virus
- capable of crossing the blood-brain barrier and can cause what is known as West Nile encephalitis, West Nile meningitis, or West Nile meningoencephalitis
also known as kissing disease
a. CMV
b. EBV
c. WNV
d. HTLV-1
In adolescence and young adulthood, EBV causes infectious mononucleosis in 30% to 50% of patients
EBV has been called the “kissing disease” because the virus usually replicates in the cells of the oropharynx, possibly in infected B cells.
it causes fifth disease
a. CMV
b. EBV
c. WNV
d. Human B19 parvovirus
Human B19 parvovirus (B19)
- is a small, single-stranded DNA nonenveloped virus.
- It causes a common childhood illness called “fifth disease” and is usually transmitted through respiratory secretions.
- Fifth disease presents with a mild rash described as “slapped cheek” when occurring on the face and a lacy red rash when occurring on the trunk and limbs.
what is the common causes of bacterial contamination
a. enviroment
b. disposables
c. donor skin
d. donor blood
Common sources of bacterial contamination include DONOR SKIN AND BLOOD . Less common sources are the environment and disposables
organism that develop a malaria- type illness
a. babesiosis
b. chaga’s disease
c. ebv
d. cmv
Most cases of babesiosis are asymptomatic. Symptomatic patients usually develop a malaria-type illness characterized by fever, chills, lethargy, and hemolytic anemia
what test is is highly sensitive and specific for the detection of antibodies to T. cruzi
a. elisa
b. complement fixation
c. immunofluoresnce
d. abbott prism chagas
The test, called the Abbott Prism Chagas, is highly sensitive and specific for the DETECTION OF ANTIBODIES to T. cruzi
CHRONIC Chagas’ disease is diagnosed serologically. Such testing includes complement fixation, immunofluorescence, and ELISA.
what disease is fatal neurodegeneration that results in spongelike lesions in the brain
a. Creutzfeldt- jakob disease (CJD)
b. plasmodium
c. chaga’s disease
d. aota
Creutzfeldt-Jakob disease (CJD)
- is one of the transmissible spongiform encephalopathies (TSE).
- These are rare diseases characterized by fatal neurodegeneration that results in spongelike lesions in the brain.
which of the following has a natural immunity in malaria spp
a. sickle cell disease
b. g6pd
c. lack of duffy antigen
d. aota
answer: AOTa
Some individuals have a natural immunity to certain species of malaria, caused by a genetic alteration in their RBCs. These include persons who have sickle cell anemia or trait, G6PD deficiency, or RBCs that lack the Duffy blood group antigen
what are the parasite transmitted thru blood transfusion
a. plasmodium
b. t. cruzi
c. leishmania
d. toxoplasmosis
Parasite that can be transmitted thru blood transfusion= Trypanosoma cruzi, Babesia microti, Toxoplasmosis, Microfilaria, Leishmania spp., and Plasmodium spp. (malaria)
MicroPlasT (micro flask) BTL / Try mo Babe leismania
