pre transfusion testing Flashcards

1
Q

Pretransfusion testing begins and ends with the proper _______ of the patient sample

a, identification

b. collection
c. nota
d. aota

A

answer: identification and collection

Pretransfusion testing begins and ends with the proper _______ of the patient sample

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2
Q

greatest threat to safe transfusion therapy

a. identification
b. collection
c. wrong label
d. clerical error

A

clerical error

> A major cause of transfusion-associated fatalities is _____ resulting in incorrect ABO groupings and transfusion of ABO incompatible blood.

> Clerical error is the greatest threat to safe transfusion therapy.

> The most common cause of error is misidentification of the recipient

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3
Q

A major cause of transfusion-associated fatalities is _____ resulting in incorrect ABO groupings and transfusion of ABO incompatible blood.

a. identification
b. collection
c. wrong label
d. clerical error

A

clerical error

> A major cause of transfusion-associated fatalities is _____ resulting in incorrect ABO groupings and transfusion of ABO incompatible blood.

> Clerical error is the greatest threat to safe transfusion therapy.

> The most common cause of error is misidentification of the recipient

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4
Q

In extreme emergencies, when there is no time to obtain and test a pretransfusion sample, group __ can be used

a. o rh + packed cells
b. o rh - packed cells
c. ab rh + packed cells
d. a rh - packed cells

A

O Rh-negative packed cells

In extreme emergencies, when there is no time to obtain and test a pretransfusion sample, group __ can be used

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5
Q

Both donor and recipient samples must be stored for a minimum of ___ following transfusion

a. 7 days
b. 14 days
c. 4 days
d. 3 days

A

7 days

Both donor and recipient samples must be stored for a minimum of ___ following transfusion

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6
Q

most critical pre transfusion serologic test

a. identifying the patient
b. correct ABO grouping
c. clerical error
d. misidentification of the recipient

A

Determining the patient’s correct ABO group is the most critical pretransfusion serologic test

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7
Q

It is a final check of ABO compatibility between donor and patient

A

crossmatching

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8
Q

final step of pre transfusion compatibility testing

A

crossmatching

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9
Q

which of these two is for major crossmatching

a. psdr
b. dspr

A
major crossmatching (PSDR)
  patient serum+ donor plasma
minor crossmatching (PRDS)
  patient red cells + donor serum
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10
Q

what are the phases of crossmatching

a. immediate spin
b. antiglobulin phase
c. saline phase
d. incubation phase

A

phases of crossmatching

  1. Immediate spin crossmatching / saline phase / initial phase
  2. incubation phase
  3. antiglobulin crossmatching phase
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11
Q

which of the 3 phases in crossmatching should be performed in room temperature

a. immediate spin
b. incubation phase
c. antiglobulin phase

A

immediate spin/ saline phase / initial phase
- done at room temperature

incubation and antiglobulin phase
- done at 37’C

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12
Q

which of the 3 phases in crossmatching use nss as enhancement media

a. immediate spin
b. incubation phase
c. antiglobulin phase

A

immediate spin
- uses NSS or 22% albumin

incubation phase
- uses LISS

antiglobulin phase
- uses albumin , liss , polyethylene glycol and polybrene

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13
Q

Adding ____________ to the test system reportedly eliminates some of the false-positive reactions

a. liss
b. saline
c. polybrene
d. ethylenediaminetetracetic acid

A

Adding ethylenediaminetetraacetic acid to the test system reportedly eliminates some of the false-positive reactions

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14
Q

significant antibodies that can be detected in incubation phase

a. IgG
b. IgM
c. IgD
d. IgE

A

B. Incubation Phase
• Done at 37’C incubation
• Usage of enhancement media such as: LISS -> 15 minutes (5 to 15minutes)
• Detection of clinically significant antibodies such as IgG

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15
Q

An autocontrol, consisting of the_______, may be tested in parallel with the antiglobulin crossmatch test.

a. patient rbc, donor plasma
b. patients own cells and serum
c. donors red cells, patients serum

A

C.Antiglobulin Crossmatching Phase

  • The antiglobulin crossmatch procedure begins in the same manner as the immediate spin crossmatch, continues to a 37°C incubation, and finishes with an antiglobulin test
  • Done at 37’C incubation
  • Several enhancement media may be applied to boost antigen-antibody reactions. These may include albumin, low ionic strength solution (LISS), polyethylene glycol, and polybrene
  • An autocontrol, consisting of the patient’s own cells and serum, may be tested in parallel with the antiglobulin crossmatch test.
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