blood components II Flashcards

1
Q

which of the blood components to use in patients that is already unresponsive to the antibiotics

a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate

A

GRANULOCYTE PHERESIS

Indication:
Patients with granulocyte dysfunction or myeloid hypoplasia who are unresponsive to antibiotics

storage : 20 - 24’C without agitation

shelf life : 24 hours

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2
Q

which of the blood components is to prevent bleeding in patients wiith hemophilia B

a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate

A

FACTOR IX CONCENTRATE

Indication:
Prevent or control bleeding in patients with hemophilia B or with specific factor deficiencies

Storage: 1-6 ‘C lyophilized

Shelf-life varies

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3
Q

what blood components is used for multiple clotting deficiencies

a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate

A

FACTOR VIII CONCENTRATE

Indication:
Prevent or control bleeding in hemophilia A patients.
Used for multiple clotting factor deficiencies

Storage: 1-6’C lyophilized

Shelf-life: Varies

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4
Q

what blood components is for replace lossof colloids in hypovolemic shock , severe burns

a. cryoprecipitate
b. irradiated blood
c. PPFA
d. Factor VIII concentrate

A

PLASMA PROTEIN FRACTION ALBUMIN

Indication:
Replace loss of colloids in hypovolemic shock, severe burns, or for pressure support during hypotensive episodes

Storage 2-10’C

Shelf-Life: 5 years

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5
Q

what is the shelf life for PPFA

a. 24 hours
b. 5 days
c. 7 years
d, 5 years

A

PLASMA PROTEIN FRACTION ALBUMIN

Indication:
Replace loss of colloids in hypovolemic shock, severe burns, or for pressure support during hypotensive episodes

Storage 2-10’C

Shelf-Life: 5 years

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6
Q

what blood components is for recipients of platelets selected for HLA or platelet compatibility

a. cryoprecipitate
b. irradiated blood
c. PPFA
d. Factor VIII concentrate

A

IRADDIATED BLOOD

Indication:

    - Essential for patients at risk from TA- GVHD
    - Recipients of platelets selected for HLA or platelet compatibility
    - Recipients of donor units from blood relatives

Uses: cesium 137 and cobalt 60 irradiated at 25-35 Gy dose

Expiration: RBC expires 28 days after irradiation or at the end of the storage period, whichever comes first

Storage temp: 1-6’C

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7
Q

A single unit of FFP or PF24, from whole blood collection, should contain __________ of plasma,

a. 400- 600 ml
b. 150-250ml
c. 100-400ml
d. 500ml

A

A single unit of FFP or PF24, from whole blood collection, should contain 150 to 250 mL of plasma,

FFP or PF24 prepared by apheresis colection may contain from 400- 600 ml

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8
Q

what is the plasma content in single blood donor

a. 400ml
b,. 300 ml
c. 20-70 ml
d. 70 ml

A

single blood donor
> prepared by apheresis
> contains atleast 3x10 (11) platelets
> plasma content : 300 ML
> can raise platelet 30 000 to 60000/ ul

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9
Q

how many platelet count can raise in random blood donor

a. 30 000ul
b. 60 000 ul
c. 5000 to 10000 plt
d. 30 000 - 60 000 ul

A
random blood donor
 > prepared by wholeblood
 > contains 5.5x 10(10) platelets
 > plasma content : 40-70ml  /  50-70 ml
 > can raise platelet count by 5000 to 10000 plt
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10
Q

what is the shelf life in washed platelets

a. 24 hours
b. 6 hours
c. 4 hours
d. 2 years

A

At room temp with agitation
-5 days

Stored at 1 to 6’C
-2 days

Frozen platelet
-2 years

Pooled
-4 hours

In an open system
-4hours

Washed platelets
-4 hours

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11
Q

In frozen platelets. Platelets are collected by apheresis, the cryopreservative _____________ is added, and the platelets are frozen at
-80°C.

a. adenine
b. citrate
c. rejuvesol
d. DMSO

A

frozen platelets

Platelets are collected by apheresis, the cryopreservative dimethyl sulfoxide (DMSO) is added, and the platelets are frozen at
-80°C.

The frozen platelets can be stored for up to 2 years.

Prior to transfusion, the platelets are thawed and centrifuged to remove the DMSO

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