blood components II Flashcards
which of the blood components to use in patients that is already unresponsive to the antibiotics
a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate
GRANULOCYTE PHERESIS
Indication:
Patients with granulocyte dysfunction or myeloid hypoplasia who are unresponsive to antibiotics
storage : 20 - 24’C without agitation
shelf life : 24 hours
which of the blood components is to prevent bleeding in patients wiith hemophilia B
a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate
FACTOR IX CONCENTRATE
Indication:
Prevent or control bleeding in patients with hemophilia B or with specific factor deficiencies
Storage: 1-6 ‘C lyophilized
Shelf-life varies
what blood components is used for multiple clotting deficiencies
a. granulocyte pheresis
b. factorIX concentrate
c. factor VIII concentrate
d. cryoprecipitate
FACTOR VIII CONCENTRATE
Indication:
Prevent or control bleeding in hemophilia A patients.
Used for multiple clotting factor deficiencies
Storage: 1-6’C lyophilized
Shelf-life: Varies
what blood components is for replace lossof colloids in hypovolemic shock , severe burns
a. cryoprecipitate
b. irradiated blood
c. PPFA
d. Factor VIII concentrate
PLASMA PROTEIN FRACTION ALBUMIN
Indication:
Replace loss of colloids in hypovolemic shock, severe burns, or for pressure support during hypotensive episodes
Storage 2-10’C
Shelf-Life: 5 years
what is the shelf life for PPFA
a. 24 hours
b. 5 days
c. 7 years
d, 5 years
PLASMA PROTEIN FRACTION ALBUMIN
Indication:
Replace loss of colloids in hypovolemic shock, severe burns, or for pressure support during hypotensive episodes
Storage 2-10’C
Shelf-Life: 5 years
what blood components is for recipients of platelets selected for HLA or platelet compatibility
a. cryoprecipitate
b. irradiated blood
c. PPFA
d. Factor VIII concentrate
IRADDIATED BLOOD
Indication:
- Essential for patients at risk from TA- GVHD - Recipients of platelets selected for HLA or platelet compatibility - Recipients of donor units from blood relatives
Uses: cesium 137 and cobalt 60 irradiated at 25-35 Gy dose
Expiration: RBC expires 28 days after irradiation or at the end of the storage period, whichever comes first
Storage temp: 1-6’C
A single unit of FFP or PF24, from whole blood collection, should contain __________ of plasma,
a. 400- 600 ml
b. 150-250ml
c. 100-400ml
d. 500ml
A single unit of FFP or PF24, from whole blood collection, should contain 150 to 250 mL of plasma,
FFP or PF24 prepared by apheresis colection may contain from 400- 600 ml
what is the plasma content in single blood donor
a. 400ml
b,. 300 ml
c. 20-70 ml
d. 70 ml
single blood donor
> prepared by apheresis
> contains atleast 3x10 (11) platelets
> plasma content : 300 ML
> can raise platelet 30 000 to 60000/ ul
how many platelet count can raise in random blood donor
a. 30 000ul
b. 60 000 ul
c. 5000 to 10000 plt
d. 30 000 - 60 000 ul
random blood donor > prepared by wholeblood > contains 5.5x 10(10) platelets > plasma content : 40-70ml / 50-70 ml > can raise platelet count by 5000 to 10000 plt
what is the shelf life in washed platelets
a. 24 hours
b. 6 hours
c. 4 hours
d. 2 years
At room temp with agitation
-5 days
Stored at 1 to 6’C
-2 days
Frozen platelet
-2 years
Pooled
-4 hours
In an open system
-4hours
Washed platelets
-4 hours
In frozen platelets. Platelets are collected by apheresis, the cryopreservative _____________ is added, and the platelets are frozen at
-80°C.
a. adenine
b. citrate
c. rejuvesol
d. DMSO
frozen platelets
Platelets are collected by apheresis, the cryopreservative dimethyl sulfoxide (DMSO) is added, and the platelets are frozen at
-80°C.
The frozen platelets can be stored for up to 2 years.
Prior to transfusion, the platelets are thawed and centrifuged to remove the DMSO