BLOOD PRESERVATIVES/ADDITIVES / REJUVENATION / FREEZING

Question 1

what is the shelf life for Acid -citrate dextrose (ACD)

a. 24 hrs
b. 21 days
c. 35 days
d. 42 days

Answer 1

I.PRESERVATIVES APPROVED PRESERVATIVES SHELF LIFE
> Acid –citrate dextrose (ACD)
- 21days
> Citrate-phosphate-dextrose (CPD)
- 21 days
> Citrate-phosphate double dextrose (CP2D)
- 21days
> Citrate phosphate adenine (CPDA-1)
- 35 days
> CPDA-2
- 42 day

Question 2

what is the shelf life for CP2D

a. 24 hrs
b. 21 days
c. 35 days
d. 42 days

Answer 2

I.PRESERVATIVES APPROVED PRESERVATIVES SHELF LIFE
> Acid –citrate dextrose (ACD)
- 21days
> Citrate-phosphate-dextrose (CPD)
- 21 days
> Citrate-phosphate double dextrose (CP2D)
- 21days
> Citrate phosphate adenine (CPDA-1)
- 35 days
> CPDA-2
- 42 day

Question 3

what is the shelf life for CPDA-1

a. 24 hrs
b. 21 days
c. 35 days
d. 42 days

Answer 3

I.PRESERVATIVES APPROVED PRESERVATIVES SHELF LIFE
> Acid –citrate dextrose (ACD)
- 21days
> Citrate-phosphate-dextrose (CPD)
- 21 days
> Citrate-phosphate double dextrose (CP2D)
- 21days
> Citrate phosphate adenine (CPDA-1)
- 35 days
> CPDA-2
- 42 day

Question 4

what is the shelf life for CPDA-2

a. 24 hrs
b. 21 days
c. 35 days
d. 42 days

Answer 4

I.PRESERVATIVES APPROVED PRESERVATIVES SHELF LIFE
> Acid –citrate dextrose (ACD)
- 21days
> Citrate-phosphate-dextrose (CPD)
- 21 days
> Citrate-phosphate double dextrose (CP2D)
- 21days
> Citrate phosphate adenine (CPDA-1)
- 35 days
> CPDA-2
- 42 day

Question 5

Acts as anticoagulant

a. citrate
b. dextrose
c. citric acid
d, monobasic sodium phosphate

Answer 5

citrate

• acts as anticoagulant
• chelates calcium

Question 6

substrate of atp

a. citrate
b. dextrose
c. citric acid
d, monobasic sodium phosphate

Answer 6

Dextrose

• Provides energy or glucose to RBC;
• Substrate of ATP

Question 7

lowers the pH

a. citrate
b. dextrose
c. citric acid
d, monobasic sodium phosphate

Answer 7

Citric acid

Lowers pH thus prevent caramelization

Question 8

maintain the ph during storage

a. citrate
b. dextrose
c. citric acid
d, monobasic sodium phosphate

Answer 8

Monobasic sodium phosphate
Maintains pH during storage;
necessary for maintenance of adequate levels of 2,3-DPG
Increase ATP levels

Question 9

The most commonly used anticoagulant-preservative solution for RBC is _________

A. ACD
B. CP2D
C. CPDA-1
D.CPDA-2

Answer 9

The most commonly used anticoagulant-preservative solution for RBC is CPDA-1.

Question 10

which of the following is not a component of additives

a. saline
b. adenine
c. mannitol
d. glucose

Answer 10

answer: nota

components of additives

Saline
Adeniine
Glucose
Mannitol

Question 11

which of the following component of additives acts as rbc stabilizer

a. saline
b. adenine
c. mannitol
d. glucose

Answer 11

Mannitol =Acts as a RBC membrane stabilizer

Question 12

what is AS-7

a. adsol
b. nutricel
c. SOLX
d. optisol

Answer 12

NAME STORAGE TIME
Adsol (AS-1)      -         42 days
Nutricel (AS-3)       -   42 days
Optisol (AS-5)        -   42 days
SOLX (AS-7)          -    42 days

Question 13

this is used to regenerate ATP and2-3DPG

a. preservatives
b. additives
c. rejuvination soln

Answer 13

REJUVENATION SOLUTIONS

➢ Used in some blood centers to regenerate ATP and 2,3DPG

Question 14

Red cells stored in the liquid state for fewer than____after their outdate are rejuvenated for 1 to 4 hours at 37’C with the solution

a. 3 days
b. 5 days
c. 24 hours
d. 7 days

Answer 14

Red cells stored in the liquid state for fewer than 3 days after their outdate are rejuvenated for 1 to 4 hours at 37’C with the solution