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CMED 311 > TRANS 076 Psychogenic Drugs > Flashcards

TRANS 076 Psychogenic Drugs Flashcards

1
Q

GTCS ( GRAND MAL EPILEPSY ) DOC

A 
Levetiracetam
• 250-500-1000 mg. tablet.
• 100mg./mL. injection
Lamotrigine
• 25-100-200 mg. tablet
Phenytoin
• 30-100 mg. capsule
• 30mg./ 5mL. susp.
• 50 mg./mL. ampule IV

LLP

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2
Q

TRIGEMINAL NEURALGIA DOC

A

Carbamazepine
• 200-400 mg. tablet
• 100 mg./5mL. syrup

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3
Q

FEBRILE CONVULSION( CHILDREN ) DOC?

A

Phenobarbital
• 15-30-60-90 mg. tablet
• 130mg./mL IV/IM

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4
Q

NEUROPATHIC PAIN / POST-HERPETIC NEURALGIA

A

Gabapentin

• 100-300-400 mg. capsule

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5
Q

SMEI (SEVERE MYOCLONIC EPILEPSY IN INFANCY –

DRAVET’S S.)

A 
Stripentol
• 250-500mg. capsule
Valproate Na
• 250 mg. tablet
• 250mg./ 5mL. syruo
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6
Q

LENNOX-GASTAUT’S SYNDROME

A 
Lamotrigine
• 25-200 mg. tablet
Topiramate
• 25-200 mg. tablet
• 15-25 mg. capsule
Rufinamide
• 200-400mg. tablet
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7
Q

ABSENCE EPILEPSY (PETIT MAL )

A 
Ethosuximide
• 250 mg. capsule
• 250 mg./ mL. syrup
\+ Valproate Na
• 250 mg. tablet
• 250 mg./5 mL. syrup
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8
Q

EPILEPSY IN PREGNANCY AND MENSTRUATION

A

Acetazolamide
• 250 mg. tablet
• 500 mg. capsule

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9
Q

STATUS EPILEPTICUS

A

Diazepam

• 5 mg./ mL. IV PUSH (20-30 mg.) @ 15 MIN.

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10
Q

INFANTILE SPASM

A

Clonazepam
• 2 mg. tablet
Clobazam
• 15-25 mg. tablet

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11
Q

MEDICAL / SITUATIONAL INSOMNIA

A

Zolpidem
• 10 mg. tablet
Eszopiclone
• 1-2-3 mg. tablet

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12
Q

GERIATRIC INSOMNIA

A

Triazolam

• 0.125- 0.25 mg. tablet

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13
Q

ANXIETY NEUROSIS

A

Buspirone

• 5 – 10 -15 – 30mg. tablet

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14
Q

OVERDOSE TOXICITY OF BENZODIAZEPINES

A

Flumazenil

• 100mcg./mL. ampule IV

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15
Q

METHANOL TOXICITY

A

Ethanol/ Fomepizole

• 1mg./mL. vial IV

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16
Q

FEMORAL TO POPLITEAL BY-PASS SURGERY

CARDIOVASCULAR RISKS

A 
Propofol
• 10 mg./mL.
• 20-50mL. vial / ampule. IV
\+ Fentanyl
• 50mcg./mL. ampule IV
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17
Q

OPD MINOR SURGERY

A

Ketamine

• 50mg./mL. vial IM/IV

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18
Q

MAJOR SURGERY ( NO CARDIOVASCULAR RISKS)

A

Isoflurane
• 100-250mL. bottle
Enflurane
• 250mL. bottle + N20 GAS

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19
Q

PRE-MEDICATION ( SKELETAL MUSCLE RELAXATION)

A 
Succinylcholine
• 20 mg/mL IV
Rocuronium
• 10 mg/mL
• 2.5-5-10ml. amp. IV
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20
Q

SPINAL ANESTHESIA (KNEE ARTHROPLASTY)

A

Bupivacaine 0.5%

• 5-10mL amp. per vial local inf. (No cardiotoxicity )

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21
Q

SPINAL ANESTHESIA ( WITH CARDIOTOXICITY )

A 
Lidocaine
• 1-2% 5-50. vial local inf.
• 5% ointment,
• 10% spray
• 4% topical solution
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22
Q

LOCAL ANESTHESIA FOR BURN WOUNDS

A 
Benzocaine
• 6% cream
• 20% gels
• 20% ointment
• 0.8% lotion
• 20% spray
• 20% liquid
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23
Q

IV CATHETERIZATION PRIOR TO VENIPUNCTURE

A

EMLA (Lidocaine + Prilocaine)

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24
Q

MPTP-INDUCED PARKINSONISM

A

Rasagiline

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25
Q

PATHOLOGIC PARKINSONISM

A 
Pramipexole (D3)
• 0.125 – 1.5mg tablet
• 0.375 – 4.5mg. ER tablet
Ropinirole (D2)
• 0.25 – 5mg tablet.,
• 2- 12 mg. ER tablet
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26
Q

STAGE-FRIGHT TREMOR

A

Propranolol

• 10-40-80mg tablet or capsule

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27
Q

HUNTINGTON’S DISEASE

A 
Haloperidol
• 500mcg.-1.5 – 2 – 5 –10 -20mg. tablet
• 5mg./mL. ampule IM
Olanzapine
• 5-10mg. tablet
• 10mg. vial IM
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28
Q

SYDENHAM’S CHOREA

A

No Treatment
D2-Blocker Symptomatic –
O FLUPHENAZINE
• 25mg./mL. ampule/vial IM/SC

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29
Q

TICS (GILLES DE LA TOURETTE’S SYNDROME)

A 
Haloperidol
• 500mcg.
• 20mg. tablet
Pimozide
• 1-2mg. tablet
Clonidine
• 75-150mcg. tablet
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30
Q

RESTLESS LEG SYNDROME

A

Pramipezole
• 0.125 -4.5mg. tablet
Ropinirole
• 0.25 – 12mg. tablet

31
Q

WILSON’S DISEASE

A

N-Acetyl-Penicillamine

• 25mg./ bottle crystals PO

32
Q

The most common psychotic illness

A

SCHIZOPHRENIA

33
Q
  • D2/5-HT2

* Block dopamine 2 more than serotonin 2

A

Phenothiazines

34
Q

examples of Phenothiazines

A

Chlorpromazine
Thioridazine
Fluphenazine
Thiothixene

35
Q

Causes these effects: type of Phenothiazines

A

Thioridazine

36
Q

Type of Phenothiazines that causes tardive dyskinesia

A

Fluphenazine

37
Q

Haloperidol, Risperidone, MISC: what drug classs?

A

Butyrophenone

38
Q

o Very potent drug with a high incidence of extrapyramidal side effect
o Parkinsonism: most common AE

A

• Haloperidol

39
Q

best drug among the new atypical drug

A

Clozapine

40
Q

causes Hypotension

• Hyperprolactinemia

A

Risperidone

41
Q

causes • QT prolongation on ECG which leads to ventricular arrhythmia

A

Ziprasidone

42
Q

causes • Weight gain
• Hyperglycemia
• Hypercholesterolemia
• No agranulocytosis

A

Olanzapine

43
Q

o Block histamine 1 producing hypotension,

A

Queiapine

44
Q

o Prolonged QT which leads to ventricular arrhythmia

A

• Ziprasidone

45
Q

• Most novel among the new/atypical drug (Academically

A

Dihydrocarbostyril

46
Q
  • Life-threatening due to hypersensitivity to extrapyramidal side effect characterized by muscle rigidity and hyperthermia
  • Treatment: diazepam, dantrolene, bromocriptine, diphenhydramine (BEST) hyperthermia: cooling
A

▪ Neuroleptic malignant syndrome (NMS)

47
Q
  • Best stabilizer for mania (drug of choice)
  • Toxic drug, less potent, high dose
  • Block enzyme GSK-3, IP3-IP2-IP1 + DAG, PGMut
  • Teratogenic: Ebstein’s Anomaly of the heart (Category D)
A

Lithium CO3

48
Q

Combination of the best drugs for Bipolar Disorder

A

• Olanzapine + Fluoxetine + Quetiapine

49
Q

Li+-Induced Diabetes Insipidus: DOC is

A

Amiloride

50
Q
  • Inhibits reuptake of norepinephrine and serotonin (NET, SERT)
  • Class 1A Anti-arrythmia
A

Tricyclics (TCA)

51
Q
  • Anti-Ach

* 2ND DOC for Major Depression

A

Amitryptiline

52
Q

what drug class?

A

ANTI-SEROTONIN/5HT2-MODULATORS

53
Q
  • ADHD in children (Secondary)
  • DOC for cigarette smoking cessation
  • Seizures 2nd:
  • Obesity/Weight loss
  • Block reuptake of Dopamine 3+ transporter
A

Bupropion

54
Q
  • Norepinephrine and serotonin transporter are inhibited (NET/SERT)
  • DOC for depression and neurologic pain
  • Fibromyalgia: pain in the muscle
A

SSNRI

55
Q
  • 1ST DOC in MDD
  • Anxiety
  • ADR: Premature Ejaculation, Bulimia
A

SSRI (SELECTIVE-5HT-REUPTAKE-INHIBITORS)

56
Q
  • The best/ No. 1 SSRI

* PMDD / Bulimia Nervosa

A

Citalopram / Escitalopram

Fluoxetine

57
Q
  • 3RD DOC for MDD

* ADR: HPN Crisis, Serotonin syndrome

A

MAO-A/B-INHIBITORS

58
Q

what drug class • Phenelzine /Isocarboxazid

A

MAO - A

59
Q

what drug class?

• Selegiline

A

Selegiline

60
Q

Anorgasmia is seen in what drug?

A

Tranylcypromine

61
Q

SSRI adverse effect?

A

o Loss of sexual f. Libido, arousal, orgasm

62
Q

SNRI: adverse effect?

A

o HPN and cardiotoxicity

63
Q

o Sedation
o Priapism
o Hepatic failure (Nefazo)

which adverse effects

A

5HT2 - M

64
Q

o Parkinsonism (Amoxapine) which adverse effects?

A

Tetra./Uni.:

65
Q

which adverse effect? o Sexual anorgasmia
o Confusion
o Delirium w/ psychosis
o Amphetamine-like effects.

A

MAOI:

66
Q

o Serotonin Syndrome, HPN CRISIS
o STROKE, M.I.

which adverse effect?

A

SSRI+MAOi

67
Q

BULEMIA NERVOSA DOC?

A

Fluoxetine

68
Q

OCD (OBSESSIVE-COMPULSIVE DISORDER )

A

CLomipramine

69
Q

SAD (SOCIAL ANXIETY DISORDER )

A

Venlafaxine

70
Q

CHRONIC PAIN DISORDER (FIBROMYALGIA)

A

Milnacipran

71
Q

PMDD ( PRE-MENSTRUAL DYSPHORIC DISORDER )

A

Sertraline

72
Q

SMOKING CESSATION

A

Buproprion

73
Q

ENURESIS IN CHILDREN

A 
Imipramine
• 25-50mg. tablet
• 75-150mg. capsule
Duloxetine
• 20-50mg. capsule
74
Q

SEDATION – HYPNOSIS IN MDD

A

Trazodone

CMED 311 (47 decks)

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