TRANS 068: Sleep Disorders Flashcards

1
Q

what sleep induces EEG “ripples” in the
hippocampus and association cortex that
play a role in consolidating memories

A

nREM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

INTERMEDIATE SLEEP DEPRIVATION what will be the results?

A
  • More burn out
  • Worsened depression & anxiety
  • Less resilience
  • Lack of a sense of wellness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Long term sleep deprivation what are the results?

A

• Correlates with less resistance to stress and immune function
• Correlates with obesity, Type 2 Diabetes, and atherosclerotic
diseases
• Degenerative Disease
 Correlate with dementia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

People with Poor [NREM/REM] sleep are more likely to develop dementia and Alzheimer’s disease

A

REM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

If you get the most [REM/NREM] sleep, your will actually have longer life than if you are in the bottom percentile

A

REM

Short REM sleep= short life expectancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how long is a sleep cycle?

A

90 mins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

in what sleep that when we wake up, we will feel we are at our best?

A

REM sleep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

All OTC sleep aids*, alcohol, barbiturates, most benzodiazepines, narcotics and anesthetics (including propofol) inhibit [REM/NREM] sleep.

A

REM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most sleepy times of day:

A

3-6am

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When you live in a place with no lighting, your circadian rhythm will stay in sync with the sun/daytime.
 When you have artificial light, your brain chooses when to sleep.

which statement is true?

A

BOTH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CAUSES OF EXCESSIVE SLEEPINESS

A

• Too little sleep
o Fragmented sleep
o Circadian rhythm disturbance

• Other conditions that masquerade as fatigue
o Mood disorder/burnout
o Hypothyroidism
o Medications or other substances

• Primary sleep disorders
o Obstructive Sleep Apnea
o Parasomnias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

• Most young adults require_______sleep cycles. _______ hrs of sleep each night (52 hrs/wk)

A

5-6

7.5 – 9 hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

• Being awakened during sleep that disrupts sleep cycles also leads to fatigue. T or F?

A

T

• Knowing you MAY be awakened changes sleep patterns
o Examples: Nursing Moms
o Physicians being on call

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q
  • Increased following sleep deprivation

* Occurs after being asleep for 30mins while in deep (slow wave) sleep

A

Sleep drunkenness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
• AKA
o Sleep inertia
o Sleep confusion
• Symptoms
o Confusion
o Amnesia
A

Sleep drunkenness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

CIRCADIAN RHYTHM SLEEPINESS happens when?

A
  • Jet lag
  • Shift work
  • Physicians on call
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Blue spectrum light [decreases/increases] melatonin production and hence decreases sleepiness
o Especially in children and adolescents

A

decreases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q
  • Gadgets themselves can disrupt sleep

* Content is stimulating T or F?

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Secondary causes of sleepiness?

A

Mood disorders

Metabolic derangements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how does sleep lead to mood d/o?

A
  • Anxiety and depression disrupt sleep
  • Early morning awakening
  • Lack of sleep worsens mood disorders
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

one of the cardinal symptoms of mood disorde

A

insomnia

22
Q

You cannot effectively treat depression or anxiety unless you re-establish normal sleep/wake cycles. T or F?

A

T

23
Q

The essential thing is getting the [NREM/REM] sleep or else, no matter what you do, if the patient is depressed or anxious, they will not be able to overcome their mood disorders.

A

REM

24
Q

What kind of medicine re-establish normal REM sleep?

A

SSRI

25
Q

what drug interfere with the natural sleep cycles.

A

Narcotics and barbiturates

26
Q

what metabolic derangements interferes with sleep?

A
  • Hypothyroidism
  • Most metabolic abnormalities
  • Many medications and drugs
27
Q
 One of the most common primary sleep disorder?
• Loud snoring
• Breathing cessation
• Abrupt awakenings gasping
• Excessive daytime sleepiness
• Morning headaches
A

Obstructive sleep apnea

28
Q

Factors that lead to obstructive sleep apnea?

A
• Factors:
o Affects up to 10% of people over the age of 50
o Obesity
o Men>women
o Older age, HTN, smoking
29
Q

Untreated OSA1 shortens life expectancy by up to____ years.

A

4

30
Q

Tx of OSA?

A
  • Weight loss
  • Exercise
  • Avoid alcohol, sedatives, smoking
  • Sleep on side, not back
  • CPAP2
  • Dental Device
  • Uvulopalatopharyngoplasty
31
Q

Cutting off the uvula

A

Uvulopalatopharyngoplasty

32
Q

Loss of hypothalamic neurons that produce hypocretins (orexins)
• Associated with changes in HLA-DQB1
• Leads to instability of REM sleep

A

Narcolepsy Cataplexy

33
Q

REM sleep instead of coming mid(?)-late at the end of your 90-min sleep cycle, tends to come in at times you are not expecting it.

A

Narcolepsy Cataplexy

34
Q

sudden attacks of sleepiness

A

Narcolepsy

35
Q

sudden loss of muscle tone while awake

A

Cataplexy

36
Q

In [REM/NREM] sleep, all the muscle tone are turned off, so even though you are dreaming, you don’t move your arms/legs.

A

REM

37
Q

In __________, you don’t go to sleep, you’re just falling down, you can’t move and then you gradually get up.

A

cataplexy

38
Q

vivid dreams are known as

A

Hypnogogic Hallucinations

39
Q

transient paralysis while awakening
 Lasts for a bout a minute or two. The first time that it happens, you are panic stricken. A horrible feeling to have. You don’t die of sleep paralysis.

A

Sleep paralysis

40
Q

Tx for narcolepsy cataplexy

A
  • Treat with good sleep hygiene
  • Antidepressants
  • Na Oxibate
41
Q
• About 1%
• More common
o >50 years of age
o Men
o Parkinson’s Disease and MSA
• Easy to awaken
• Remember dream

what diosrder?

A

REM BEHAVIORAL D/o

42
Q
o Deep sleep
o Children
o Seem awake but amnestic
o Inconsolable screaming
o Very hard to awaken

what sleep disorder?

A

Night terror

43
Q

o Deep sleep
o Children
o Seem awake but amnestic
o Walking, eating, driving, having sex

waht sleep diosrder?

A

Sleep walking

44
Q

• Patient feels like they want to move legs
• Worse at night
 This is a lack of dopamine phenomenon

A

RESTLESS LEG SYNDROME

45
Q

Tx for Restless leg syndrome?

A

• Iron supplementation
• Exercise
• Dopamine agonists
o Ropinirole, Rotigotine, and Pramipexole

46
Q

How to improve sleep in general?

A

• Exercise daily
o Most people do better if strenuous exercise is not just before bedtime
o As little as 10 minutes of moderate exercise helps
• Expose yourself to sunlight during the day
• Address mood disorders
• Naps
o 30 to 90 minutes okay if that is part of your routine
o Not close to bedtime
• Avoid:
o Drugs
o Cigarettes
o Alcohol
o Sleeping pills
o Large meals close to bedtime

47
Q

How to listen to your circadian rhythm?

A
  • Go to bed when you are tired
  • As much as possible, maintain a regular bedtime and a regular awakening time
  • Follow a relaxing bedtime routine
  • Plan for sleep based on 90 minutes
  • Never “toss and turn” in bed for longer than 20 minutes
48
Q

how to make bedrooms pleasant?

A
• Dark
• Comfortable temperature
• Well-ventilated
• Quiet
o White noise
• Comfortable bed
• Use bedroom only for sleeping and sexual intimacy
o Do not treat the bedroom as a lounge
49
Q

how to schedule worry time?

A

• Suggestions:
o Schedule a time to worry prior to bedtime
o Resolve to write down concerns that you think about so you can deal with them in the morning

50
Q

how to practice relaxation

A

• Relax muscles
• Think of three things you are thankful for
o Write them down
• Imaging a pleasant scene

51
Q

Some bedtime routine?

A
• Think of three things you are thankful for
o Thank God for them
• Set aside problems
o Turn them over to God
• Contemplate
o God’s wonderfulness