Top Drug Test 2 Flashcards

1
Q

A 54-year-old male is prescribed a 7-day course of clarithromycin for a lower respiratory tract infection. You are dispensing this medication for him and notice an interaction with one of his medicines, atorvastatin. Which is the most appropriate advice to provide?

A

There is a significant interaction between Clarythromycin and atorvastatin.

1.Avoid taking them together if possible
2. Can consult a doctor to adjust the dose or switch to a different statin ie rosuvastatin

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2
Q

A 74-year-old woman calls the surgery asking for your advice. She has noticed her urine has discoloured recently and appears a darker yellow-brown colour. She has no other symptoms. She wonders if this is due to one of her medications. Which of her medications, could be a possible cause of her urine discolouration?

A

Urine discolouration can be caused by:
1. Metronidazole.
2. Levodopa.
3.rifampicin
4. Some multivitamins.
But also dehydration

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3
Q

A 36-year-old male asks for your advice. He is currently taking amoxicillin 500mg TDS for a chest infection. He is on day 2 of treatment and is experiencing intermittent diarrhoea. He asks whether he should stop the antibiotics. What is the most appropriate advice to provide?

A

Do not stop the antibiotics immediately

Intermittent diarrhoea can be a common side-effect of antibiotics for example, amoxicillin

  1. Differentiate the stage of diarrhoea, is it mild or severe?
  2. If mild then they continue the antibiotics but stay hydrated and potentially take probiotic supplements if discussed with the healthcare provider.
  3. If the diarrhoea becomes severe or is accompanied by bloody stools and or a high fever, they should stop the antibiotics and contact their healthcare provider immediately.
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4
Q

A 62-year-old man presents to your pharmacy with athlete’s foot. He has experienced this in the past but has not had it for some years now. He wishes for a treatment to be provided over the counter. Which of the following would you recommend?

A
  1. Clotrimazole - canesten
  2. Miconazole - Daktarin
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5
Q

A 64-year-old female who lives with COPD, is experiencing thick sticky mucus in her airways and consequently has a regular productive cough. Her GP has excluded any sinister causes and wishes to prescribe carbocisteine, however you advise this is not appropriate due to her past medical history. What contraindicates the use of carbocisteine?

A

It can irritate the gastrointestinal tract and may exacerbate conditions like gastritis or peptic ulcers

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6
Q

A 34-year-old woman presents to the pharmacy with a sore eye; you diagnose bacterial conjunctivitis. Which eye drops preparations would be the most appropriate to recommend?

A

Chloramphenicol

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7
Q

A 52-year-old female is prescribed dihydrocodeine for pain relief following a surgical procedure. What is NOT a common side-effect of dihydrocodeine?

A

Rash, urinary retention, hypotension, addiction

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8
Q

A 43-year-old woman is diagnosed with a respiratory tract infection by her GP. They ask for your advice as she is allergic to penicillins and macrolides, both have a history of causing anaphylaxis. She asks which antibiotics she could prescribe for her?

A

Doxycycline
Clindamycin

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9
Q

A 83-year-old man is diagnosed with COPD. He has been commenced on a short-acting beta 2 agonist, but also requires a long-acting muscarinic antagonist to provide better control during the day. Which agents would be suitable to prescribe?

A

Tiotropium - spiriva

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10
Q

A 52-year-old female is prescribed trimethoprim 200mg BD for 3 days for an uncomplicated UTI. Which would contraindicate use of trimethoprim?

A

Pregnancy, severe impairment, folate deficiency, allergy, severe liver disease

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11
Q

Fluoxetine drug interaction

A

Phenelzine

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12
Q

Digoxin drug interaction

A

Quinidine

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13
Q

Sildenafil drug interaction

A

sosorbide Mononitrate

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14
Q

Potassium chloride drug interaction

A

Spironolactone

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15
Q

Clonidine drug interaction

A

Propranolol

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16
Q

Theophylline drug interaction

A

Ciprofloxacin

17
Q

Doxycycline drug interaction

A

iron (ferrous)

18
Q

Warfarin drug interaction

A

naproxen.

19
Q

Clarithromycin drug interaction

A

simvastatin

20
Q

Methotrexate drug interaction

A

NSAIDs

21
Q

Omeprazole drug interaction

A

clopidogrel