Colloids WS W4

Question 1

True or flase : Inhalation delivery provides a slower onset of drug action compared to oral delivery.

Answer 1

False

Question 2

True are flase : The choice of excipients in aerosol formulations is primarily determined by the drug being delivered.

Answer 2

F - determined by the delivery of the drug. Somme drugs can have the same excipients

Question 3

True or false : emulsions are more thermodynamically stable than suspensions.

Answer 3

False

Question 4

True or false : Non-ionic surfactants are generally better emulsifying agents than ionic ones in
pharmaceutical applications.

Answer 4

True

Question 5

True or false : The Bancroft rule states that low HLB surfactants are suited for oil-in-water emulsions.

Answer 5

False

Question 6

What is the ideal particle size range for pulmonary drug delivery

Answer 6

1-5 microns

Question 7

What is the primary advantage of using inhalation delivery from drugs like salbutamol

Answer 7

Rapid onset of action

Question 8

What is the primary role of lactose in dry powder inhalers (DPI’s)

Answer 8

Carrier for drug particles

Question 9

Which of the following mechanisms is responsible for the deposition of large particles in
the lungs?

Answer 9

Sedimentation

Question 10

Why are emulsions considered thermodynamically unstable?

Answer 10

They have dynamic liquid-liquid interfaces

Question 11

What is the role of surface tension in emulsions

Answer 11

Determines the energy cost of creating or maintaining new surface area

Question 12

What is a zwitterion surfactant?

Answer 12

Egg lecithin

Question 13

What does the HLB value of a surfactant indicate ?

Answer 13

Wether its more soluble in oil or water