COPD WS W4

Question 1

What is a characteristic of COPD

Answer 1

Damage to cilia

Question 2

Key cell types

Answer 2

Neutrophil
CD8+
Goblet

Question 3

Pharmacological effect of muscarinic agonists

Answer 3

mimic the action of acetylcholine at muscarinic receptors,

Decrease heart rate

promoting peristalsis and smooth muscle contraction. Via M3

cause constriction of bronchial smooth muscle. Via M3

Contraction of the bladder smooth muscle in GIT

Question 4

Pharmacological effect of muscarinic antagonists

Answer 4

block the action of acetylcholine at muscarinic receptors

slow the heart rate

decrease peristalsis and motility, leading to constipation

bronchodilation and reduced mucus secretion,

Question 5

Atropine

Answer 5

is a muscarinic antagonist - bronchodilation

Question 6

SAMA example

Answer 6

Ipratropium

Question 7

Likely side effect of the use of inhaled anti-muscarinic drugs

Answer 7

Dry mouth

Question 8

LAMA example

Answer 8

Tiotropium bromide

Question 9

SABA example

Answer 9

Albuterol/salbutamol

Question 10

LABA example

Answer 10

Salmeterol