Respiratory Medicines Workshop W3 Flashcards
Delivery of therapeutic agents into the respiratory tract is mainly to treat local (true or false?).
True
asthma is a local condition
Treatment of asthma involves deposition of the drug in the alveoli region (true or false?).
False
It is the bronchi and bronchioles
Pulmonary drug delivery is associated with a slow onset of action (true or false?).
False
Rapid onset as delivery is direct to airway
The larger the size of the drug particles, the higher levels of deposition in the lower airways (true or false?).
False
Large particles deposit in the upper airway
The vapour pressure of the propellant influences the deposition of the drug particles within the respiratory tract (true or false?).
True
Too much pressure means particles accelerate
Meter dose inhalers require the drug to be soluble within the propelled system system (true or false?).
True
The volume of the propellant is in MDI release upon actuation is dictated by a metered value (true or false?).
True
Control how much drug is given to patient
The mass median aerodynamic diameter of the drug particles in a dry powder inhaler should be less than 5 µm
True
Lactose is commonly used within dry powder inhalers to mask the bitter taste of the API (true or false?).
False
The pH of a nebuliser solution should be higher than five
True
More acidic trigger airway irritation
Nebuliser solution should be hypotonic (true or false?).
False
Isotonic
Nebuliser solution should be hypotonic (true or false?).
False
Isotonic
All inhalers are bad for the environment (true or false?).
False
All inhalers are bad for the environment (true or false?).
False
The patient inhaler technique is only important when using an MDI
False
