Thyroid and antithyroid drugs?

Question 1

What are the three hormones the thyroid gland secretes?

Answer 1

Thyroxine, tri-iodothyronine, and clacitonin

Question 2

What is the role of the parathyroid gland?

Answer 2

It produces hormones that naintain calcium in the ECF

Question 3

What is the function of the thyroid gland?

Answer 3

Regulates macronutrient metabolism, help with growth and development, control the thermoregulatory centre, and affects cardiovascular, neuromuscular and endocrine systems.

Question 4

What is hypothyroidism and what are the three levels?

Answer 4

This is a deficiency in thyroid hormones. The three levels are primary which is abnormal thyroid, secondary when pituitary gland is dysfunctional, and tertiary which is when hypothalamus doesn’t secrete thyrotropin hormone which helps thyroid secrete.

Question 5

What is congenital hypothyroidism?

Answer 5

This is when there is low secretions of thyroid hormone during youth resulting in delayed growth and development

Question 6

What is myxedema?

Answer 6

This is low secretions of thyroid hormone in adulthood and causes delayed metabolism

Question 7

What is a goitre?

Answer 7

This is when there is an enlargement of the thyroid gland because of overstimulation of the thyroid through oversecretion of TSH

Question 8

WHat are symptoms of hypothyroidism?

Answer 8

Cold intolernace, weight gain, depression, fatigue

Question 9

What is the main example of a thyroid replacement drug?

Answer 9

Levothyroxine

Question 10

What is the MOA of thyroid replacement drugs?

Answer 10

They replace the hormones the thyroid gland is unable to produce.

Question 11

What is the main adverse effect of levotyroxine?

Answer 11

Cardiac dysrhythmias

Question 12

What are important things to consider when giving thyroid replacement drugs?

Answer 12

Do not discontinue abruptly, give at the same time everyday, and don’t interchange brands

Question 13

What is hyperthyroidism and what causes it?

Answer 13

This is when the thyroid secretes too much thyroid hormone. It is caused by graves disease, thyroid storm, multinodular disease

Question 14

What is the overall effect of hyperthyroidism?

Answer 14

It has an overall effect of increased metabolism

Question 15

What are antithyroid drugs?

Answer 15

They are used to treat the excess thyroid hormone from an overactive thyroid gland

Question 16

What are the main adverse effects of antityroid drugs?

Answer 16

They may result in liver and bone marrow toxicity and leukopenia

Question 17

What is the main drug treatment for hyperthyroidism?

Answer 17

Propylthiouracil (PTU)

Question 18

How should a nurrse go about care for a pregnant mother with hypothyroidism?

Answer 18

The mom should continue to take treatment for the hypothyroidism to promote fetal growth and development

Question 19

What type of food should be avoided for patients on antithyroid medications?

Answer 19

They should avoid foods high in iodine like seafood and soysauce