Therapeutics COPY Flashcards

1
Q

OBJ: What are the use category definitions for antimicrobials?

A
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2
Q

OBJ: Which antimicrobials are the most effective for BRD?

A
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3
Q

OBJ: Which are the most and least expensive antimicrobials?

A
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4
Q

OBJ: How do you trade off cost, efficacy, number or administrations, and withdrawal time?

A
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5
Q

OBJ: How do injectable and in-feed antimicrobials compare?

A
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6
Q

OBJ; What about lactating dairy cattle and cattle intended for dairy production?

A
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7
Q

define Prevention

A
  • Prophylaxis
  • administration of an antimicrobial to an individual animal to mitigate the risk for acquiring disease or infection that is anticipated based on history, clinical judgement, or epidemiological knowledge
  • Administration of an antimicrobial to a group of animals, none of which have evidence of disease or infection, when transmission of existing undiagnosed infections or the introduction of pathogens is anticipated based on history, clinical judgement or epidemiological knowledge
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8
Q

Define Control (Metaphylaxis)

A
  • Administration of an antimicrobial to an individual animal with a subclinical infection to reduce the risk of the infection becoming clinically apparent, spreading to other tissues or organs, or being transmitted to other individuals
    • Use of antimicrobials to reduce the incidence of infectious disease in a group of animals that already has some individuals with evidence of infectious disease or evidence of infection
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9
Q

Define treatment

A
  • Administration of an antimicrobial as a remedy for an individual animal with evidence of infectious disease
  • Administration of an antimicrobial to those animals within the group with evidence of infectious disease
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10
Q

Define growth promotion

A
  • Use of a drug to enhance average daily gain and/or feed efficiency
  • Medically important antimicrobials are illegal for this use in the US
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11
Q

What antimicrobials are approved for single injection in cattle?

A
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12
Q

What antimicrobials are approved for multiple injections in cattle?

A
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13
Q

What antimicrobials are approved for use in lactating dairy cows

A
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14
Q

What antimicrobials are approved for metaphylaxis use in cattle?

A
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15
Q

What antimicrobials can be used extra-label for BRDC?

A
  • All poor choices
    • Aminoglycosides
      • Gemtamicin - 18mo slaughter withdrawal (FARAD)
      • Neomycin
    • Lincomycin/spectinomycin (LS50)
    • Compounded combinations
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16
Q

What does control treatment for BRD accomplish?

A

Treatment for control of respiratory disease (mass med, metaphylaxis) suppresses and delays morbidity, it does NOT prevent morbidity