Therapeutics Flashcards
Semisolid emulsion of oil in water Contain emulsifier & preservative High water content Cool & moisturise Non greasy Easy to apply Cosmetically acceptable
Cream
Semisolid grease/oil (soft paraffin) No preservative Occlusive and emollient Restrict transepidermalwater loss Greasy - lesscosmetically attractive
Ointment
Liquid formulation
Suspension or solution of medication in water, alcohol or other liquids
If contain alcohol, may sting
Treat scalp, hair-bearing areas
Lotion
Thickened aqueous lotions
Semi-solids, containing high molecular weight polymers eg methylcellulose
Treat scalp, hair bearing areas, face
Gels
Semisolids Contain finely powdered material eg ZNO Stiff, greasy,difficult to apply Protective,occlusive,hydrating Often used in cooling, drying, soothing bandages
Paste
How much emollient should you prescribe?
250-500g weekly
How much does a non-proprietary emollient cost?
£3 per 500g
(e.g. soft paraffin, emulsifying ointment, aqueous cream)
Non-proprietary cost £5-12
Corticosteroid mode of action?
Vasoconstrictive
Anti-inflammatory
Anti-proliferative
Mild steroid
Hydrocortisone
Moderate steroid
Clobetasone butyrate
Modrasone
Potent steroid
Betamethasone valerate
Very potent steroid?
Clobetasol propionate
Medication you could use in lichen planus?
Steroid
How much ointment do you need to cover whole body?
20-30g
Side effects of topical steroids
Steroid rosacea
Perioral dermatitis
Fixed telangiectasia