Sara eczema

Question 1

Contact allergic hypersensitivity type?

Answer 1

Delayed type 4

Question 2

Drug related hypersensitivity?

Answer 2

Type 1/4

Question 3

Histology of drug related dermatitis?

Answer 3

Spongiotic dermatitis and eosinophils

Question 4

Cause of lichen simplex?

Answer 4

Physical trauma to skin - scrating

Question 5

Histology of stasis dermatitis?

Answer 5

Spongiotic dermatitis and extravasation of RBCs

Question 6

Immunopathology of contact allergic dermatitis?

Answer 6

langerhans cells in epidermis –>
Th cells in dermis –>
Th cells migrate to lymphatics & regional nodes where antigen presentation is amplified

Question 7

Cells that infiltrate the dermis in dermatitis?

Answer 7

Loads of specifically sensitised T cells! :)

Question 8

Non-specific physical irritation rather than a specific allergic reaction?

Answer 8

Irritant (contact) dermatitis

Question 9

Irritant contact dermatitis to urine?

Answer 9

Nappy rash

-sparing of flexures

Question 10

Percentage of children affected by eczema?

Answer 10

up to 25%

Question 11

UK diagnostic criteria for eczema

Answer 11

Itching plus 3 or more:
Visible flexural rash*
History of flexural rash*
Personal history of atopy 					(or first degree relative if under 4 yo)
Generally dry skin 
Onset before age 2 years

*cheeks and extensor surfaces in infants

Question 12

Other types of eczema associated with atopy?

Answer 12

Discoid eczema

Photosensitive eczema

Question 13

Type of eczema secondary to hydrostatic pressure, oedema and red cell extravasation?

Answer 13

Stasis eczema

Question 14

Pompholyx eczema appearance?

Answer 14

Spongiotic vesicles