Structure and Function 2 Flashcards
Pigment producing dendritic cells
Melanocytes
Contain melanosomes
Melanocytes
Eumelanin
Brown or black
Phaeomelanin
Red, yellow
What do melanosomes do?
Convert tyrosine to melanin pigment
What protects the nuclear DNA in basal cells?
Melanin caps ;)
How are melanosomes transferred to adjacent keratinocytes?
Transferred via dendrites :)
What is Nelson’s syndrome?
Excess melanin stimulating hormone is made by the pituitary
A tumour of the melanocyte cell line
Malignant melanoma
These cells are mesenchymal in origin and come from the bone marrow
Langerhans cells
Where do langerhans cells come from?
Mesenchymal origin - bone marrow
Where are the langerhans cells in the epidermis?
They are at the prickle cell layer in the epidermis
Where are langerhans cells found?
Epidermis, dermis and lymph nodes
Which cell would you find Racket organelles (Birbeck granules) in?
Langerhans cells
basal
between keratinocytes & nerve fibres
mechanoreceptors
Merkel cells
Where are merkel cells found?
Between keratinocytes and nerve fibres
What type of infection causes Merkel cell cancer?
Viral infection
What makes up the pilosebaceous unit?
Epidermal component plus dermal papilla
Anagen
Catagen
Telogen
Hair follicle phases of growth
Anagen
Growing
Catagen
Involuting
Telogen
Resting
Hormones which have an effect on hair growth
Thyroxine
Androgens
Alopecia areata
Autoimmune hair loss
Rate of nail growth?
0.1mm per day
Which season do nails grow most?
Summer
