Structure and Function 4

Question 1

Steroid-sulphatase deficiency ichthyosis inheritance?

Answer 1

X-linked

Question 2

Metabolic functions of the skin

Answer 2

Vitamin D metabolism
Thyroid hormone metabolism
Defence against chemicals, drugs, pollutants & sunlight

Question 3

Hydroxycholecalciferol?

Answer 3

This is how Vitamin D3 is stored in the LIVER

then converted to 1-25-dihydroxycholecalciferol in the kidney

Question 4

Which wavelength range is responsible for converting cholecalciferol into Vitamin D3?

Answer 4

290-320nm ultraviolet

Question 5

Percentage of T4 to T3 conversion that occurs in thyroid/skin?

Answer 5

20% of this conversion occurs in thyroid gland

80% in peripheral (to thyroid) tissues including skin

Question 6

Name a disease that occurs due to hosts insufficient immune response

Answer 6

Crusted scabies
Tubercoid leprosy (Hansen's disease)

Question 7

Tubercoid leprosy

Hansen’s disease

Answer 7

Skin condition characterised by solitary skin lesions that are asymmetrically distributed

Skin lesions that may be faded/discolored
Growths on the skin
Thick, stiff or dry skin
Severe pain
Numbness on affected areas of the skin
Muscle weakness or paralysis (especially in the hands and feet)
Eye problems that may lead to blindness
Enlarged nerves (especially those around the elbow and knee)
A stuffy nose
Nosebleeds
Ulcers on the soles of feet