Structure and Function Flashcards

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1
Q

Basal cell layer

A

Usually one cell thick
Small cuboidal
Lots of intermediate filaments (keratin)
Highly metabolically active

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2
Q

Prickle cell layer

A

Larger polyhedral cells
Lots of desmosomes (connections)
Intermediate filaments connect to desmosomes

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3
Q

KGPBD

A
Keratin layer
Granular layer
Prickle cell layer
Basal layer
Dermis
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4
Q

Which layer would you find keratohylin granules (contain structural filaggrin & involucrin proteins) and odland bodies (lamellar bodies)?

A

Granular layer :)

think about it, they sound like granules!

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5
Q

Origin of ‘cornified envelope’

A

Granular layer

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6
Q

Cell nuclei are lost by this layer?

A

Granular layer

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7
Q
Corneocytes: overlapping non-nucleated cell remnants
Insoluble cornified envelope
80% keratin & filaggrin
Lamellar granules release lipid
Tight waterproof barrier
A

Keratin layer

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8
Q

Which layer would you find corneocytes?

A

Keratin layer

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