the ventricles and CSF Flashcards
ventricles
connected internal cavities in the brain filled with CSF
CSF
protein rich fluid essential for brain function
lateral ventricles are in the __________________
prosencephalon
third ventricle is in the __________________
diencephalon
third ventricle is in the __________________
hindbrain
does CSF flow bilaterally
no, unilaterally
development of the ventricles
what does the brain develop from
neural tube
developmentally the brain consists of …
- forebrain
- midbrain
- hindbrain
forebrain parts
- cerebrum
- thalamus
- hypothalamus
hindbrain parts
- pons
- medulla oblongata
- cerebellum
brainstem parts
- midbrain
- hindbrain
primary divisions of the neural tube
- prosencephalon
- mesencephalon
- rhombencephalon
- spinal cord
prosencephalon subdivisions
- telencephalon
- diencephalon
telencephalon main constituent parts and cavities
- olfactory lobes
- cerebral hemispheres
- lateral ventricles
- rostral portion of the 3rd ventricle
diencephalon main constituent parts and cavities
- epithalamus
- thalamus
- hypothalamus
- infundibulum
- most of the 3rd ventricle
mesencephalon main constituent parts and cavities
- colliculi/corpora quadrigemini
- cerebral peduncle
- cerebral aqueduct
rhombencephalon subdivisions
- metecephalon
- myelencephalon
mesencephalon subdivisions
mesencephalon
metencephalon main constituent parts and cavities
- cerebellum
- pons
- 4th ventricle
myelencephalon main constituent parts and cavities
- medulla oblongata
- 4th ventricle
spinal cord subdivisions
spinal cord
spinal cord main constituent parts and cavities
- spinal cord
- central canal
two lateral ventricles communicate through the ___________________ ______________ __ _______ with the ______________ ________________
interventricular foramen (of Monro); third ventricle
what makes up the body of the lateral ventricles
anterior, posterior, and inferior horns
roof of the lateral ventricles
under surface of the corpus callosum
floor of the lateral ventricles
- body of the caudate nucleus
- lateral margin of the thalamus
medial wall of the lateral ventricles
septum pellucidum
anterior boundary of the lateral ventricles
anterior column of the fornix
posterior boundary of the lateral ventricle
the anterior end of the thalamus
what projects into the body of the ventricle
choroid plexus
in which lobe is the inferior horn of the lateral ventricles located
temporal
how do the lateral ventricles communicate
- separated by the septum pellucidum
- do not communicate
how are the third and fourth ventricles connected
cerebral aqueduct (aqueduct of sylvius)
what bounds the third ventricle
thalamus and hypothalamus
what is the fourth ventricle continuous with
- the central canal
- three foramina in its roof with the subarachnoid space
fourth ventricle foramen names and location
- foramen of Lushka (x2 lateral)
- Magendie (x1 posterior)
terminal ventricle
small dilation at the inferior end of the central canal
CSF color
colorless
what is in CSF
- inorganic salts (similar to those found in blood plasma)
- glucose
- protein
- lymphocytes
CSF pressure range
8-15 mmHg
total volume of CSF
135-150 mls
CSF functions
- protection
- buoyancy
- waste product excretion
- endocrine medium for the brain
CSF function - protection
buffers the brain
CSF function - buoyancy
net weight of brain is reduced
CSF function - waste product excretion
one-way flow of CSF to the blood takes away potentially harmful metabolites, drugs, and substances
CSF function - endocrine medium for the brain
- transport hormones to entire brain
- hormones released into CSF is carried to remote sites of the brain
where is CSF formed
- choroid plexuses of the lateral, third, and fourth ventricles
- ependyma surrounding capillaries and loose connective tissue
ependyma
cuboidal epithelial cells
how much CSF is produced daily
500 ml
plaque that causes Alzheimers
beta amyloid
how many times is CSF recycled and why
- 4x/day
- clean out metabolites and toxins
into where does most CSF drain
into the blood through arachnoid granulations in the superior sagittal sinus
flow of CSF
the subarachnoid space through aperatures, into the cisterna magna (via lateral and medial aperatures)
what facilitates the flow of CSF
- pulsations of the cerebral and spinal arteries
- vertebral column movements
- respiration, coughing
- changing body position
how does CSF flow into the bloodstream
small protrusions of the arachnoid through the dura mater into the venous sinuses of the brain
arachnoid villi job with CSF
one way valves, prevent backflow
what pressure gradient allows CSF to flow into the bloodstream
CSF pressure > venous pressure
hydrocephalus
a neurological disorder caused by an abnormal buildup of CSF in the ventricles
hydrocephalus causes
- overproduction of CSF
- obstruction in the ventricular system
- problems with CSF absorption
types of hydrocephalus
- communicating hydrocephalus
- non-communicating hydrocephalus
communicating hydrocephalus
- full communication between ventricles and subarachnoid space
- usually defective absorption of CSF
- sometimes insufficient venous drainage
- rarely CSF overproduction
non-communicating hydrocephalus
- lack of communication between ventricles and subarachnoid space
- CSF flow is obstructed
how is hydrocephalus decompression achieved
insert a shunt that connects the ventricles to the jugular vein or the abdominal peritoneum
shunt
hollow tube surgically placed in the brain to help drain CSF
papilledema
swelling of the optic nerve
papilledema cause and result
- CSF pressure increase compresses the thin walls of the retinal vein as it crosses the subarachnoid space to enter the optic nerve
- optic disc bulging forward and optic disc edema
what does persistent papilledema lead to
optic atrophy and blindness
what is CSF pressure increase usually caused by
- meningitis
- increase in brain volume (edema, tumor, cerebral abscess, or hematoma)
cloudy CSF meaning
presence of polymorphonuclearleukocytes
polymorphonuclearleukocytes
excessive protein quantity
increase in white cells in CSF meaning
encephalitis
encephalitis
inflammation of the meninges
an increase in protein in CSF meaning
a change in vascular permeability allowing protein to get into CSF
blood in CSF meaning
contamination brought about by puncture of a vertebral vein by a spinal tap needle
xanthochromia definition
yellow coloration
xanthochromatic CSF meaning
presence of oxyhemaglobin in the fluid following subarachnoid hemorrhage
spinal tap
spinal fluid is collected for testing