olfactory and limbic systems Flashcards

1
Q

olfactory sensory neurons

A
  • no circuitry or synapses in the epithelium
  • receptors have axons (thin, unmyelinated, slow) that project directly to the olfactory bulb
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2
Q

how often do receptors die and be replaced

A

every 60 days

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3
Q

can sensory cells regenerate

A

yes

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4
Q

where are first order neurons located

A

between receptors and olfactory bulbs

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5
Q

second order neurons synapse with ? in ?

A

tuftal and mitral cells; olfactory glomerulus

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6
Q

bipolar neurons

A

second order neurons

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7
Q

olfactory nerve components

A

bipolar nerves with unmyelinated axons

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8
Q

principal neurons of the olfactory bulb

A

mitral and tuftal cells

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9
Q

aromatic compounds recognize ?

A

particular receptors

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10
Q

aromatic compounds travel where ?

A

particular glomerulus

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11
Q

glomerulus

A

basic processing component of the olfactory bulb

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12
Q

polysynaptic structure of olfactory bulb function

A

ensuring conversion of specific olfactory impulses to the mitral and tuft cells

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13
Q

periglomerular and granular cell function

A

mediate local and lateral inhibition

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14
Q

where is the olfactory tract located

A

in the olfactory sulcus

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15
Q

what does the olfactory tract contain

A

the axons of mitral and tufted cells

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16
Q

where does the olfactory tract run

A

to olfactory trigone

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17
Q

second order olfactory nerves transmit info to ? via ?

A

olfactory stria; olfactory tract

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18
Q

olfactory tract projects via ? to ? on the base of the frontal/medial temporal lobe

A

stria; olfactory cortex

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19
Q

largest olfactory stria

A

lateral olfactory stria

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20
Q

lateral olfactory stria

A
  • to primary olfactory cortex (piriform cortex)/parahippocampal gyrus on temporal lobe
  • conscious awareness (recognition) of odor
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21
Q

uncinate fit

A
  • temporal lobe epilepsy
  • seizures with elaborate and multiple sensory, motor, and/or psychic components
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22
Q

what precedes uncinate fits

A

hallucinations of disagreeable odors

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23
Q

types of olfactory strias

A
  • lateral olfactory stra
  • medial olfactory stria
  • intermediate olfactory stria
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24
Q

medial olfactory stria

A
  • to septal area/lower, posterior part of the medial surface of the frontal lobe
  • olfactovisceral reflexes
25
Q

intermediate olfactory stria

A
  • olfactory tubercle
  • reward behavior
26
Q

anterior commissure function

A

connects two halves of the olfactory system (anterior to the columns of the fornix)

27
Q

what does the insula recieve

A

taste input from the medial part of vpm of thalamus (flavor)

28
Q

orbitofrontal cortex function

A

furthers conscious smell olfactory perception

29
Q

olfactory pathway

A
30
Q

how does the limbic system operate

A

influencing endocrine system and autonomic nervous system

31
Q

limbic system functions

A
  • control emotions and emotional responses
  • mood
  • motivation
  • pain and pleasure sensations
32
Q

limbic system links complex goal directed behavior to …

A

primitive, instinctive behavior, important for survival

33
Q

cortical areas of limbic system

A
  • septal area
  • cingulate gyrus
  • parahippocampal gyrus
34
Q

deeper structures of limbic system

A
  • hippocampal formation and fornix
  • amygdala
  • mammillary bodies
  • anterior nuclei of the thalamus
35
Q

hypothalamus

A
  • maintain homeostasis
  • stimulation produces behaviors seen in other limbic areas (rage, aggression, docile behaviors)
36
Q

thalamus

A
  • relays sensory information to limbic system
  • connects brainstem to cerebrum/relay center
37
Q

amygdala

A
  • emotion, reproduction, fear, aggression
  • modulation of autonomic and neuroendocrine systems
  • stimulation can produce rage
38
Q

hippocampus

A
  • memory conversion
  • associative learning and memory (memory acquisition and short term memory)
39
Q

limbic structures are interconnected by …

A
  • fornix
  • mammillothalamic tract
  • stria terminalis
  • cingulum
40
Q

hippocampus damage results in

A

amnesia

41
Q

amygdala lesion result

A

docile behavior

42
Q

kluver-bucy syndrome

A
  • ignore social conventions
  • bilateral lesions of the anterior temporal lobe
43
Q

how is the amygdala connected to the hypothalamus

A

stria terminalis

44
Q

what is the amygdala directly connected to

A

thalamus and neocortex

45
Q

septal area components

A
  • septal nucleus
  • septum pellucidum
  • small portion of neocortex
  • relief of fear, docile behavior, stress
46
Q

septum pellucim

A

thin membrane between 2 lateral ventricles

47
Q

septal area lesion result

A

rage and aggressive behavior

48
Q

what is the septal area connected to

A

hypothalamus and hippocampus (fornix)

49
Q

cingulate gyrus

A
  • overlies corpus callosum
  • control of emotional and visceral responses, aggressive behavior
50
Q

how does the cingulate gyrus connected with the hypothalamus

A

mammillothalamic tract

51
Q

what is the cingulate gyrus connected to

A

anterior nuclear group of the thalamus through thalamic radiations

52
Q

papez circuit

A
53
Q

how are papez circuit functions mediated

A

through hypothalamus and autonomic nervous system

54
Q

diseases related to the limbic system

A
  • acquired disorders
  • dementia
  • neuropsychiatric disorders
55
Q

acquired disorders (limbic system)

A
  • violence
  • suicidal behavior
  • agitation
  • mood swings
56
Q

dementia

A

degeneration of limbic system structures (may be genesis of other neurodegenerative disorders)

57
Q

neuropsychiatric disorders

A
  • anxiety
  • schizophrenia
  • psychopathic disorders
58
Q

olfactory nerve versus olfactory tract

A
  • olfactory bulb is a relay station for the transmission of the impulse coming from the olfactory nerve
  • from the olfactory bulb, impulses then travel through the olfactory tract
  • olfactory tract divides into the medial and lateral olfactory striae, then connects to the olfactory cortex