The Oral Environment Flashcards
what is present within the salivary glands to produce the saliva
specialised acini
what are the oral fluids
- saliva
- gingival crevicular fluid
- oral bacteria
- food debris
- epithelial cells
where is the gingival crevicular fluid found
in the crevice between the tooth and the gingiva known as the sulculus
what are the main brackets of function of the oral fluids
digestive and protective
what are the protective functions of the oral fluids
cleansing
mucosal protection
buffering
remineralisation
antimicrobial
how do you measure pH
logarithmic scale - every unit of pH change is a factor of 10
why do buffers within the ph have a constant of association known as the pKa
because the buffer can only take the hydrogen ions in a certain range in order to stop the drop in pH
what is remineralisation
this is when the tooth loses the mineral and is able to gain it back
how does the saliva make teeth stronger
can provide calcium phosphate to the tooth structure when it has been demineralised
what does fluoride come from mainly for our mouths
toothpaste
why does thrush often occur after a course of antibiotics has been taken
the microorganism that causes thrush is found in the fungi family and therefore is not killed by the antibiotics. the antibiotics also kill all the flora in the mouth, including the good ones, reducing protection.
what produces mucous in the respiratory tract
globular cells
what produces mucous in the mouth
the salivary glands
what can happen to the experience of eating when there is reduced salivary flow
things don’t taste as nice and can be harder to chew
what are the digestive functions of the oral fluids
taste
digestive enzymes
lubricating bolus
what is an example of a digestive enzyme found within the oral fluid
amylase
why is it important that the saliva lubricates bolus for chewing and swallowing
it needs to be soft enough to be swallowed
what is the link between saliva and oral diseases
saliva is important for defence roles and a reduced flow can cause a number of oral health problems due to absence of various protective enzymes
why can decreased secretion of saliva occur
there are many reasons for this, such as salivary gland diseases or diseases of other glands
what is xerostomia
dry mouth, and a prominent symptom for patients with salivary gland disease
on what surfaces of the tooth can the increased incidence of dental caries be viewed when there is reduced saliva flow
the buccal and labial surfaces.
why are the buccal and labial surfaces of the tooth usually safe from dental caries if saliva flow is normal
they are easily cleansed by the movement of mastication
what are salivary glands
exocrine glands that produce serous and or mucous secretions.
what is the name of the arrangement of salivary glands
tubulo acinar arrangement
what are the minor salivary glands
these are a more diffuse collection of glandular tissue lying in the lamina propria of the following areas of the oral cavity:
- buccal
- labial
- lingual
- palatal - both soft and hard palate
what are the major salivary glands
these are more distinct and identifiable and are the following
- parotid
- sublingual
- submandibular
they are paired salivary glands - two of each
describe the salivary gland structure
there are acini that clump together to form capsules, the secondary arrangement
intercalated tubules are found between the acini
there are also striated tubules
all of these collect together into the main collecting duct
this is the structure of a single lobe of a salivary gland
why is it important that there are striated tubules
there are certain changes in the saliva at this area
what are the myoepithelial cells found in salivary glands
these are cells that can be found in the glands that look or react as muscle cells
what do acini produce
saliva
where do the acini produce the saliva into
the lumen, which joins onto the intercalated tubules
what is the difference between the serous and mucous acini
mucuos acini require a machinery that will produce the mucous and be kept inside the acinus. the process of keeping proteins in the acinus gives the inner portion of the cell a frothy arrangement, and the nuclei are usually pushed away from this froth. there is a big difference in colour between the froth and the nuclei.
in comparison, the serous acini lack these proteins and therefore do not have froth pushing away the nuclei.
describe the acinus of mixed acini
they have a mucous arrangement and a serous arrangement
what are the salivary gland secretions of the major salivary glands
parotid is serous
submandibular is mixed
sublingual is mucous
what secretion is released by the parotid salivary gland
serous
which secretion is released by the submandibular salivary gland
mixed
which secretion is released by the sublingual salivary gland
mucous
which secretion is released by the buccal minor salivary gland
mucous
which secretion is released by the labial salivary gland
mucous
which secretion is released by the lingual salivary gland
serous and mucous - not a mixed secretion though
which secretion is released by the palatal salivary gland
mucous
what is gingival crevicular fluid
fluid from the epithelium that lines the gingival crevice that can also be called sulcular fluid
relevant for the health of the gingiva - if there is inflammation there will be concentrations of this fluid
what is the sulcus
the gingival crevice
how many ml of saliva are produced while sleeping
10
how many ml of saliva are produced while awake or resting
250
how many ml of saliva are produced while eating
360
how many ml of saliva are secreted on average every day
620
what do the contributions of the different salivary glands vary depending on
the degree of stimulation
why is it important to brush our teeth before going to sleep
there is much less saliva being produced and therefore there is less protective function so the fluoride is required to protect the teeth further
why is reduced saliva flow associated with oral diseases
absence of various protective components
where is the sublingual salivary gland located
under the tongue
where is the submandibular salivary gland located
base of the mandible, below the sublingual
where is the parotid salivary gland located
under the ear and in front of it - not behind it
where do the striated ducts run into
the main collective duct
when does flow of the gingival crevicular fluid increase
when there is inflammation
what is the average range of daily salivary flow
500-700
which salivary gland secretes the majority of saliva when sleeping
the submandibular, at 70%
what is the percentage contribution of the sublingual gland when sleeping
15%
what is the percentage contribution of the parotid gland when sleeping
0%
what is the percentage contribution of the submandibular gland when sleeping
70%
what is the percentage contribution of the minor salivary glands when sleeping
15%
what is the percentage contribution of the parotid salivary gland when awake
20%
what is the percentage contribution of the submandibular gland when awake
72%
what is the percentage contribution of the sublingual gland when awake
4%
what is the percentage contribution of the minor glands when awake
4%
what is the percentage contribution of the parotid gland when stimulated
50%
what is the percentage contribution of the submandibular gland when stimulated
40%
what is the percentage contribution of the sublingual gland when stimulated
2%
what is the percentage contribution of the minor glands when stimulated
8%
which salivary gland produces the most saliva when awake
submandibular
which salivary gland produces the most saliva when stimulated
the parotid gland
what are the factors that affect unstimulated salivary flow rate
- state of hydration
- previous stimulation
- circadium rhythms
- circannual rhythms
- medications
- salivary gland disease
what is the composition of the inorganic component of saliva
99.5% is water
0.2% is ions
what is the composition of the organic component of saliva
0.3% mainly proteins with little carbohydrate or lipid
does the salivary composition of the glands vary
yes, usually varies depending on flow rate.
there is greater bicarbonate ion concentration at higher flow rates and is important for buffering plaque acids
when is the bicarbonate concentration of saliva greater
when there are higher flow rates
what are the three main categories of function that the saliva is found related to
the teeth, microorganisms and food
how does the function of saliva related to food
- taste
- digestion
- bolus formation
how does the function of saliva related to teeth
- buffering
- decreasing demineralisation
- remineralisation
- lubrication
how does the function of saliva relate to microorganisms
antibacterial
antifungal
antiviral
what are the digestive enzymes found within the saliva that contribute to food digestion
- amylase
- protease
- lipase
- dnaase
- rnaase
how does saliva contribute to the taste of food
gustin, zinc and water
how does saliva contribute to bolus formation in the mouth
contains mucins and water
how does saliva function in buffering
contains bicarbonate, phosphate and proteins
how does the saliva function in reducing demineralisation of teeth
contains mucins, calcium and phosphate ions
how does saliva function in remineralising teeth
contains calcium and phosphate ions
how does saliva function in lubrication of teeth
mucins and PRG
how does the saliva function in being antiviral
contains cystatins, mucons, immunoglobins and SLPI
what does the saliva contain that allows for being antifungal
histatins, chromagranin A and immunoglobins
what does the saliva contain that gives it an antibacterial function
- lysozome
- lactoferrin
- calprotectin
- lactoperoxidase
- immunoglobins
- chromogranin A
- cystatins
- histatins
- vegh
- slpi
what ions can be found in saliva
fluoride
calcium
thyocyanite
bicarbonate
phosphate
what does fluoride function as in the saliva
- antibacterial
- forms fluorapatite
- promotes remineralisation
what does calcium and phosphate function as in the saliva
remineralisation
what does thyocyanite function as in the saliva
antibacterial
what does bicarbonate and phosphate function as in the saliva
buffering
when is bicarbonate most effective
at high flow rates when the its at its highest
when is phosphate important as a buffer
at rest
when are proteins important as buffers in the saliva
they have a limited effect and their main buffering action occurs at pH lower than 5
when are bacterial ammonia ions important as buffers in the saliva
they have a role in buffering plaque acid
what are the salivary buffers
bicarbonate
phosphates
proteins
bacterial ammonia