Salivary Flow pt 2 Flashcards

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1
Q

what is the normal unstimulated flow of saliva

A

0.2-0.4ml/min

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2
Q

what is the normal stimulated flow of saliva

A

1-5ml/min

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3
Q

what is the unstimulated flow of saliva in patients with xerostomia

A

less than 0.1ml/min

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4
Q

what is the stimulated flow of saliva in patients with xerostomia

A

less than 0.5ml/min

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5
Q

for saliva flow to fall below 50% of the normal levels, what must happen

A

there must be loss of function of more than one major salivary gland

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6
Q

what are some general conditions that could affect the salivary glands

A

fluid and electrolyte loss

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7
Q

how many drugs cause dry mouth

A

over 400

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8
Q

what is the BNF

A

british national formulary

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9
Q

what is smooth surface caries related to

A

reduced salivary flow and clearance

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10
Q

what are the oral functions that become impaired by xerostomia

A

chewing
swallowing
speaking
diminished taste perception

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11
Q

what are some protective components that are lost due to decreased salivary flow

A
  • antimicrobial agents
  • less buffering
  • mucins and other proteins
  • gustin
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12
Q

are the absolute flow rates set

A

no they can vary - consider the functional aspects

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13
Q

which questions, when answered with yes, suggest hypofunction of the salivary glands

A
  • does your mouth feel dry when eating a meal
  • do you have difficulty swallowing any foods
  • do you sip liquids to help swallow dry food
  • does the amount of saliva in your mouth feel too little
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14
Q

how can you manage xerostomia if there is still a functional salivary gland

A

chewing or through drugs

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15
Q

which drugs stimulate saliva flow

A

sialogogues

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16
Q

when there is no functioning gland tissue remaining in someones mouth, what can be used to manage the xerostomia

A
  • taking saliva substites that are either mucin or cellulose based.
  • water alone is not effective
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17
Q

is the saliva flow static

A

no

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18
Q

where is salivary flow higher in the mouth

A

in lower lingual regions

19
Q

where is salivary flow lower in the mouth

A

labial and buccal regions

20
Q

where are cariogenic sugars retained longer in the mouth

A

in regions where the flow is slowest

21
Q

how does saliva flow in the mouth

A

horizontally, it moves toward the back of the mouth if it is from the sublingual gland
submandibular saliva washes over the anterior teeth with aid from minor mucous secretions
parotid washes over the posterior teeth

22
Q

which factors affect clearance

A

salivary film velocity and location in the mouth

23
Q

what are the important oral health aspects of clearance in the mouth

A
  • removal of harmful materials
  • retention of beneficial materials
24
Q

what is dawes rule

A

stimulus leads to salivary flow, making the residual volume accumulate and trigger swallowing, and the residual is then returned

25
Q

how is clearance of harmful substances increased

A

by high salivary flow

26
Q

how is retention of beneficial substances improved

A

by reduced salivary flow rates

27
Q

what are the beneficial substances that we do not want to be cleared from the mouth

A

fluoride and chlorhexidine

28
Q

why should fluoride tablets be sucked on rather than chewed

A

to prevent stimulation of saliva flow, and keep clearance to a minimum

29
Q

what is the stephan curve

A

a graph of the plaque pH change over time

30
Q

how do plaque microorganisms generate acid

A

by metabolising sugars like sucrose

31
Q

how does gum stimulation affect pH

A

it rises by 0.5 pH unit and this persists for a long time

32
Q

what type of gum increases salivary pH to above 1 pH unit

A

bicarbonate containing gum

33
Q

does gum chewing remove plaque

A

no

34
Q

what are the types of alternative sweeteners

A
  • bulk caloric, low caloric
  • non calory, high intensity
35
Q

what are the bulk, cariogenic sweeteners

A

sucrose
fructose
glucose
lactose

36
Q

what are the low caloric sweetenders

A

mannitol
sorbitol
xylitol

37
Q

what are the non caloric sweeteners

A

aspartame
cyclamates
saccharin
sucralose

38
Q

which sweetenders are non cariogenic relative to sucrose

A

the low caloric and non caloric sweeteners

39
Q

at what flow rate will patients begin to complain of dry mouth

A

50%

40
Q

name the stimulants that go to the salivary centres to increase saliva flow

A
  • higher centres
  • masticatory afferents
  • gustatory afferents
41
Q

what does sympathetic effect of salivary flow lead to

A

constriction, greater flow

42
Q

what does parasympathetic effect of salivary flow lead to

A

dilation, greater flow

43
Q

describe the two stage mechanism of ductal modification

A
  • primary saliva is modified as it passes through striated ducts
  • reabsorption of sodium and chlorine
  • secretion of potassium and bicarbonate
  • final saliva hypotonic to plasma
  • some proteins secreted by ducts