The Lymphoid system Flashcards
Where do T cells go to mature?
thymus
Where do B cells go to mature?
bone marrow
What are the primary lymphoid tissues?
bone marrow and thymus
What are the secondary lymphoid tissues?
lymph nodes; spleen; waldeyers ring; epithelio-lymphoid tissues
What are the functions of the lymphoid system?
filtration of circulatory fluids and location for cells of the immune system; return lymph to the circulation
Where do afferent channels to the lymph nodes drain
?
lymph through the capsule into the peripheral sinus
How do arteries and veins serving the lymph node enter and exit the node?
hilum
How is lymph filtered in the lymph nodes?
filtered thorugh the node parenchyma
What cell populations are found in lymph nodes?
B cells; T cells; macrophages; APCs; dendritic cells; endothelial cells
Where are plasma cells found in lymph nodes?
medulla
What part of the lymph node are B cells associated with?
follicles and germinal centres
Which cell type is CD20 a marker for?
B cell
Which cell type is CD3 a marker for?
T cell
What tends to stimulate a predominant B cell resposne in a lymph node?
auto-immune conditions; infection
What tends to stimulate a predominate phagocytic resposne?
tumours