Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Haematology > Normal Erythrocytes > Flashcards

Normal Erythrocytes Flashcards

1
Q

What is the function of the spleen?

A

removes fragile old RBCs from circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Aside from the spleen, what other organ gets rid of old RBCs?

A

phagocytic cells of the liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the globins of haemoglobin broken down into?

A

amino acids which enter the blood stream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the haem group (minus iron) converted to?

A

bilirubin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What happens to iron?

A

binds to transferrin i nthe blood and recycled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is seen with polychromatic erythroblasts?

A

Hb appears in cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is seen in the orthochromatic erythroblast?

A

nucleus shrinks; full complement of Hb in cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What makes up the buffy coat?

A

platelets and WBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is haematocrit?

A

volume of RBCs as percentage of total blood volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the form of glutathione in the cell?

A

reduced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are free radicals?

A

highly reactive molecules with unpaired electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the main reactive species?

A

hydrogen peroxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the problem with excessive free radiclas?

A

damage of cellular structures and enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the function of glutathione?

A

prevents buidlup of hydrogen peroxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the 3 forms of CO2 in the blood?

A

dissolved; carbamino-haemoglobin; bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What enzyme mediates CO2 +H2O —bicarb?

A

carbonic anhydrase

17
Q

What is the function of the chloride/bicarb exchange?

A

preserves potential

18
Q

What happens to the hydrogen ions when bicarb is produced?

A

buffered by deoxygenated Hb

19
Q

What is co-operativity?

A

influence that binding of a ligand to one protomer has on the bidning of a ligand to another protomer in an oligomeric protein

20
Q

What is the difference in repsonse to 2,3-DPG between HbF and HbA?

A

HbF has a lower affinity for 2,3DPG than HbA

Haematology (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions