Test 3: Wk11: 7.1 Gas Transport and Diffusion - Dasgupta

Question 1

there is a direct correlation between the partial pressure of gasses and

Answer 1

the concentration of gasses

Question 2

0.3 % Vol O2 in plasma = PaO2 100 mmHg

then 0.6% Vol O2 in plasma =

Answer 2

200 mmHg

Question 3

O2 is carried in what two forms in the blood

Answer 3

dissolved in plasma and bound to hemoglobin

Question 4

O2 solubility

Answer 4

very insoluble

Question 5

amount of O2 dissolved in arterial blood in lungs

Answer 5

0.3 ml O2 /100ml

3 ml O2 / L

0.3 vol %

Question 6

partial pressure of oxygen is due to dissolved oxygen in plasma not

Answer 6

oxygen bound to hemoglobin

Question 7

each molecule of Hb binds to — molecules of O2

Answer 7

4

Question 8

majority of O2 in blood is bound to

Answer 8

Hb

Question 9

O2 available to tissues is through

Answer 9

dissolved O2

Question 10

Hb is a — for oxygen

Answer 10

buffer/ reservoir

Question 11

Capillary PO2 deoxygenated

Answer 11

40 mmHg

Question 12

gasses move

Answer 12

down partial pressure gradients

Question 13

O2 dissociates from – and goes into solution in plasma

Answer 13

Hb

Question 14

Dissolved gas diffuses — into interstitial space

Answer 14

down partial pressure gradient

Question 15

PO2 in arterial blood

Answer 15

100 mmHg

Question 16

Hb saturation arterial blood

Answer 16

97.4 %

Question 17

PO2 in venous blood

Answer 17

40 mmHg

Question 18

Hb saturation venous blood

Answer 18

75%

Question 19

Amount of oxygen bound to Hb=

Answer 19

1.34 X amount of hemoglobin X % of Hb saturated with oxygen.

Question 20

Arterial oxygen content %

Answer 20

19.8 volume %

Question 21

Venous oxygen content %

Answer 21

14.8 volume %

Question 22

volume % of O2 unloaded to tissue

Answer 22

5%

Question 23

Hb protects tissue from

Answer 23

large fluctuations in O2 partial pressure

Question 24

In anemia PVO2 is

Answer 24

decreased

Question 25

Hb affinitiy for Co is —

Answer 25

200x more than O2

Question 26

O2 Capacity

Answer 26

maximal amount of oxygen Hb is capable of carrying. Does not include dissolved oxygen

Question 27

O2 Capacity in polycythemia (high Hb)

Answer 27

increased

Question 28

O2 capacity in Anemia (Low Hb)

Answer 28

decreased

Question 29

O2 capacity in CO poisoning

Answer 29

decreased

Question 30

O2 capacity =

Answer 30

O2 content - O2 dissolved

Question 31

Hb saturation =

Answer 31

Hb saturation = O2 bound to Hb / O2 capacity x 100

Question 32

Pulse Oximeter measures

Answer 32

saturation of Hb by using wavelengths

Question 33

Normal Arterial pH

Answer 33

7.36-7.45

Question 34

Normal Arterial PO2

Answer 34

80-100mmHg

Question 35

Normal Arterial PCO2

Answer 35

35-45

Question 36

Normal Arterial HCO3

Answer 36

23-28 meg/ml

Question 37

Normal Arterial O2 saturation

Answer 37

95-100%

Question 38

P50

Answer 38

partial pressure of O2 when Hb is 50% saturated

approx 26mmHg

Question 39

Hb curve shift right

Answer 39

lower affinity for O2

Question 40

Hb curve shift left

Answer 40

higher affinity for O2

Question 41

What happens to Hb and P50 during exercise

Answer 41

Hb unloads more O2

P50 increases

Question 42

CO2 transported 3 ways

Answer 42

dissolved in plasma
as HCO3
bound to Hb

Question 43

CO2 can diffuse times as rapidly as O2

Answer 43

20

Question 44

Hambruger/ Chloride Shift

Answer 44

Cl goes into RBC as HCO3 leaves to maintain electroneutrality

reverse in lung

Question 45

CO2 reacts with deoxygenated Hb to form

Answer 45

carbamino compounds

Question 46

% CO2 transported as carbamino compounds

Answer 46

5%

Hb has loww affinity for CO2