Anti TB Drugs Summary Slides Flashcards
Rifampin adrs
GI upset
drug-drug interactions
orange discoloration
hepatotoxicity
Isoniazid adrs
neurotoxicity
peripheral neuropathy
hepatotoxicity
Pyrazinamide adrs
GI Upset
Hyperuricemia
Hepatoxicity
Ethambutol adrs
Neurotoxicity
CNXII - vertigo
Nephrotoxicity potential
RIPE therapy
6mos RIPE followed by 4mos RI
Lepromatous Leprosy
disseminated
multibacillary with loss of specific cell mediated immunity
Tuberculoid Leprosy
localized
paucibacillary with strong cell-mediated immunity
Leprosy Tx
DR.C
Dapsone, Rifampin, Clofazimine
MAC sx
fever
night sweats
wt loss
anemia
MAC usually occurs in
advanced HIV
MAC Prophylaxis regimen
Clarithromycin
Azithromycin
Alternative Rifabutin
MAC tx Regimen
Clarithromycin or Azithromycin plus Ethambutol
RIPS Therapy
6mos total
2 months RIPS followed by 4 months RI