Test 3: Wk11: 3 Histology of Pulmonary Surfaces - Dougherty Flashcards
Lobes of right lung
superior
middle
inferior
lobes of left lung
superior
inferior
Fissures of right lung
horizontal
oblique
Fissures of left lung
oblique
what are the 3 nasal cavaties
- Nasal Vestibule
- Internal Nasal Cavity
- Sinuses
what creates the 2 chambers of the internal nasal cavity
nasal septum midline
what is the nasal septum made of
hyaline cartilage and bone
internal nasal cavity bones
conchae or turbinate bones
where does skin of nose enter the nasal cavity
nares
nasal vestibule contains (2)
vibrissae
glands
Vibrissae are — and do what
nasal hairs
filter
2 Glands of the nasal vestibule
Sebaceous glands
sweat glands
where does keratinized squamous epithelium transition to respiratory epithelium
Nasal Vestibule
In the internal nasal cavity — covers all but the roof and superior concha
respiratory epithelium
The respiratory epithelium in the internal nasal cavity is made of - - - epithelium
ciliated pseudostratified epithelium
plasma cells in the lamina propria of the internal nasal cavity make
IgA
the submucosa of the internal nasal cavity contains — and — glands
mucous
seromucous
Respiratory Epithelium - Ciliated pseudostratified columnar epithelial cells contain what 5 cell types
- Ciliated Columnar Cells
- Goblet Cells
- Brush Cells
- Small Granule Cells
- Basal Cells
— cells produce mucin glycoproteins
goblet
— cells are chemosensory receptors and have sparse blunt microvilli
Brush cells
— also called Kulchitsky Cells are diffuse neuroendocrine system cells
small granule cells
— cells are mitotically active progenitor and stem cells
basal cells
cilia are made of — containing — sets
peripheral microtubule doublets
9 sets
the axoneme of cilia is the
two center microtubules
Dynein forms what on cilia
arms extending from doublets
Olfactory Epithelium is pseudostratified contain what 3 cells
- Olfactory neurons
- Supporting Cells
- Basal Cells
Olfactory epithelium olfactory neurons are — neurons
bipolar
What is the luminal pole of olfactory neurons
a dendrite with enlarged long non-motile cilia with chemoreceptors
the axons of olfactory neurons coalesce to form small nerves passing through the — to the —
cribriform plate to the olfactory bulb
Supporting cells of olfactory neurons function is —
they contain —
unclear
contain microvilli
Olfactory Glands in the olfactory epithelium are — glands responsible for —
serous glands responsible for constant fluid flow
Paranasal sinuses are lined by — respiratory epithelium with fewer — cells
thinner
goblet
The paranasal sinuses have a thin lamina propria between — and —
epithelium and bone
Glands of the paranasal sinuses are — in number
few
the 3 parts of the pharynx are
Nasopharynx
Oropharynx
Laryngopharynx/ hypopharynx
the nasopharynx is made of (60%) — mucosa and (40%) — mucosa
respiratory
squamous
the nasopharynx contains what 3 structures
Pharyngeal tonsil
auditory tube opening
seromucous glands
the oropharynx contains what 2 structures
Palatine Tonsils
Seromucous Glands
Oropharynx is contains — mucosa
squamous
Laryngopharynx contains — mucosa
squamous
The larynx contains what 2 types of cartilage and 1 bone
Hyaline cartilage
Elastic Cartilage
Hyoid Bone
Hylanine cartilage of the larynx contains 3 structures
thyroid
cricoid
inferior arytenoid cartilages
Elastic cartilage of the larynx contains what 4 structures
epiglottis
coniform
corniculate
superior arytenoid cartilage
The upper/ anterior lingual surface is made of — — epithelium
stratified squamous
the lower laryngeal surface is the transition to — epithelium
respiratory
in the larynx respiratory epithelium covers all but the — and —
lingual epiglottis and vocal cords
Epiglottis lingual surface, portion of laryngeal surface and vocal cords have — — epithelium
stratified squamous
the vocalis muscle of the larynx is comprised of
skeletal muscle
the larynx contains — glands
seromucous
the trachea is lined with — epithelium
respiratory
the trachea contains 16-20 c-shaped — — rings
hyaline cartilage rings
what muscle bridges between the ends of cartilage in the trachea
trachealis muscle
what tissue separates the cartilage rings of the trachea
Fibroelastic tissue
— is the outside covering of the tracheal
adventitia
Primary bronchi enter lung hilum with —
vessels
Secondary lobular bronchi enter pulmonary lobes
how many right? how many left?
3 right, 2 left
— bronchi is the bronchopulmonary segment of the bronchial tree
tertiary segmental bronchi
bronchioles end where
in pulmonary lobule
how many terminal bronchioles are in each lobe
5-7
the lumen of bronchi — with each branch
decreases
Primary Bronchi contain rings of cartilage. As they branch to smaller sizes, what happens to the cartilage rings
gradually replaced by plates of cartilage
The smooth muscle of bronchi is — arranged in the —
spirally
lamina propria
Bronchi contain — fibers
elastic
Bronchioles contain no
gland or cartilage
Bronchioles are intralobular airways with a diameter
less than/ equal to 1mm
Bronchioles are contain of what kind of muscle
smooth
bronchioles contain — fibers
elastic
Bronchioles transition over distance from — — — epithelium to — epithelium
ciliated simple columnar
cuboidal
Terminal bronchiole epithelium transitions from — epithelium to — cells
respiratory to club cells
club cells of terminal bronchioles are made of — — epithelium? do they have cilia
cuboidal simple epithelium
no cilia
club cells of terminal bronchioles have a — cytoplasm
granular
club cells of terminal bronchioles have what 2 exocrine functions
make surfactant
Secretory component for IgA
club cells of terminal bronchioles perform detoxification by
P450 in SER
club cells of terminal bronchioles have — enzymes
antibacterial/ ativiral
Terminal bronchiole epithelium consist of what 4 cells
- club cells
- stem cells
- Brush Cells
- DNES Small Granular Cells
the lamina propria of the terminal bronchioles contains (3)
SMCs
Autonomic Nerve Fibers
Elastic Fibers
— is the smallest anatomic subunit bound by connective tissue
Pulmonary Lobule
how many Respiratory Bronchioles per terminal bronchiole
2-3
Respiratory Bronchioles resemble terminal bronchioles but have
sac-like alveoli in walls
Alveolar Ducts are lined by
openings of alvoli
Alveolar Ducts are lined by — — epithelium (same as alveoli)
attenuated squamous epithelium
Alveolar ducts have — around each alveolar opening
smooth muscle
Alveolar Sacs are clusters of
alveoli
the thin lamina propria of alveolar sacs is mostly comprised of — and — fibers
elastic and reticulin
do alveolar sacs have smooth muscle
no
Alveolar sacs have a prominent
capillary network
Alveoli size
200 um
interalveolar Septa of alveoli contain —
fibroblasts
interalveolar Septa of alveoli contain — and — fibers
elastic and reticular
interalveolar Septa of alveoli are rich in
capillaries
Alveolar pores connect
neighboring alveoli from different bronchioles
what equalizes pressure btwn alveoli
Alveolar pores
— allows for collateral flow of air if a bronchiole is obstructed
alveolar pores
— separates blood from air
alveolar respiratory membrane Blood-air barrier
3 components of the alveolar respiratory membrane
2-3 thin alveolar lining cells
fused basal lamina btwn layers
thin capillary endothelium
Type I alveolar cells are
attenuated cells lining surface
— make up 95% of alveolar lining
Type I alveolar cells
Type I and Type II alveolar cells have — and — to prevent leakage
desmosome and tight junctions
Type II alveolar cells (septal Cells) are
cuboidal
Type II alveolar cells contains — bodies
lamellar
Lamellar bodies of Type II alveolar cells secrete
pulmonary surfactant
most Alveolar macrophages (dust cells) are removed by
mucocilary apparatus