Test 3: Wk11: 2.1 Mechanisms of Ventilation - Dasgupta Flashcards

1
Q

the — bronchus is slightly higher then then the —

A

right higher then left

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2
Q

the pleural space exerts a — pressure which makes the lungs

A

negative; stick to chest wall

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3
Q

When the diaphragm contracts and shortens it will flatted and

A

expand the volume of the thorax

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4
Q

parietal pleura is innervated by —

can they perceive pain?

A

intercostal nerves

yes, perceive pan

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5
Q

Visceral Pleura innervated by —

Can they perceive pain?

A

somatic nerves

no pain, only stretch

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6
Q

pleuritis

A

inflammation of pleural cavity

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7
Q

pleuritis causes

A

sharp severe chest pain which gets worse upon inspiration, coughing, sneezing, or laughing

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8
Q

Most common cause of pleurisy

A

viruses

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9
Q

Conduction Zone contians

A

Trachea
Bronchi
Bronchioles
Terminal Bronchioles

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10
Q

Transitional and Respiratory Zones contain

A

respiratory bronchioles
alveolar ducts
alveolar sacs

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11
Q

the airways bifurcate — times

A

~23

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12
Q

bifurcations 16-20

A

transitional zone of the lung

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13
Q

bifurcations 20-23

A

respiratory zone

extensive alveolar structures

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14
Q

anatomical dead space of the lung

A

no gas exchange - conducting zone

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15
Q

bifurcations 0-16

A

conducting zone

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16
Q

where does gas exchange occur

A

the last 4 bifurcations in the alveolar ducts and alveoli

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17
Q

Apnea:

A

Complete absence of spontaneous ventilation

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18
Q

Eupnea:

A

Normal spontaneous breathing.

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19
Q

Dyspnea:

A

Difficulty of breathing that the individual is aware of.

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20
Q

Bradypnea:

A

decrease of the respiratory rate

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21
Q

Tachypnea:

A

A rapid rate of breathing.

hyperventilation

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22
Q

Orthopnea

A

dyspnea which occurs when lying flat, causing the

person to have to sleep propped up in bed or sitting in a chair.

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23
Q

Compliance is

A

the measure of lung softness

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24
Q

Compliance =

A

delta V / delta P

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25
Residual Volume
there is always a finite amount of air in the lung
26
Pressure in the lung is measure in
cm H2O
27
atmospheric pressure =
0 cm H2O
28
gas partial pressure are expressed in units of
mmHg
29
lungs are
passive
30
energy needed to pump gas into the lungs comes from
the chest wall
31
intrapleural pressure is always --- during restive inhalation
negative
32
the recoil of the lung is
inward
33
the recoil of the chest wal is
outward
34
Functional Residual Capacity (FRC)
amount of air in the lungs when mouth is open and respiratory muscles are relaxed
35
Lung elastic recoil forces are a result of what 2 factors
1. lung tissue elastic recoil | 2. Surface tension forces
36
lung tissue elastic recoil is from
the polymer molecules that make up the lung. When mechanically inflated, they exert a recoil force
37
Surface Tension Forces are from
each alveolus is a water lined compartment where water exerts force that act to reduce the size of the surface - to collapse the lung
38
--- is the main contributor to lung recoil
surface tension
39
--- forces are responsible for surface tension
cohesive
40
within fluid forces are
balanced
41
at the surface of fluid forces are
unbalanced, the surface molecules are pulled inward
42
Laplace's Law
P = T / r/2 T = tension r = radius
43
Laplace's law states that
P is inversely proportional to radius
44
collapsed alveoli are --- but are ---
not ventilated but are perfused
45
Shunt
vascular pathway in which there is no gas exchange
46
right to left shunt
blood comes from the right side of heart and goes through the lung without gas exchange
47
surfactant is made of
90% phospholipids and 10% proteins
48
Surfactant is secreted by
alveoli type II cells
49
the primary surface tension lowering surfactant is
DPPC
50
the hydrophobic end of surfactant allows
surfactant to spread across the fluid surface
51
the hydrophilic components of surfactant
insert themselves between water molecules along the surface lowering surface tension
52
the more concentrated surfactant the more surface tension is
lowered
53
absence of surfactant lung recoil is
very high
54
Alveoli A has radius of r Alveoli B has radius of 2r both have concentration of y surfactant which has higher surface tension?
Alveoli B has higher surface tension because the same amount of surfactant is spread over a larger area 4x more surfactant in A than B surface tension of B is 4x A
55
surface tension is --- to surfactant
inversely proportional
56
Alveoli A has radius of r Alveoli B has radius of 2r which has greater pressure
Alveoli B, B will empty into A until they are equal
57
inhalation is an
active process
58
the diaphragm --- during inhalation
contracts and moves down
59
the external intercostal muscles --- during inhaltion
contract and lift ribs up
60
accessory muscles of shoulder girdle are
not involved in quiet breathing but can be used during exercise, coughing, and sneezing
61
accessory muscles in COPD and emphysema
used for inhalation
62
tripod position
physical stance used in pts with respiratory distress such as COPD bent over with hands on knees
63
normal exhalation is a
passive process
64
during exhalation the diaphragm
relaxes
65
what drives gas out of the lungs
as the diaphragm relaxes, the vol of the thoracic cage and alveoli decrease, alveolar pressure becomes positve and gas leaves
66
what 2 things happen during forced exhalation
1. internal intercostals contract | 2. abdominal muscles contract to push guts and diaphragm up
67
Boyle's Law
at constant temperature, pressure of a gas is inversely proportional to volume
68
Transmural Pressure (Ptm) =
Ptm = Palv - Ppl Palv - alveolar pressure Ppl - intrapleural pressure