Test 2 NSAIDs Flashcards

1
Q

NSAIDs

A
  • indicated for pain or arthritis

- black box warning

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2
Q

precautions of NSAIDs

A
  • heart disease
  • hypertension
  • renal impairment
  • gastrointestinal irritation
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3
Q

contraindications for NSAIDs

A

contraindicated for treatment of perioperative pain in the setting of CABG surgery

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4
Q

Motrin

A
  • ibuprofen
  • max is 1200 mg / day OTC
  • 400mg q4-6H: pain
  • 1200-3200 divided tid-qid: arthritic conditions
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5
Q

counseling points for NSAIDs

A
  • take with food: helps with the irritation

- avoid alcohol

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6
Q

Anaprox/ Anaprox DS

A
  • Naproxen sodium
  • just for (moderate) pain
  • faster peak than naproxen base
  • 550 mg, then 275 mg q 6-8 h prn
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7
Q

Naprosyn / EC-Naprosyn

A
  • naproxen base
  • just for arthrtitis
  • Naprosyn not for initial treatment of acute pain
  • 250 - 500 mg bid
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8
Q

Indocin

A
  • indomethacin
  • arthritis (all kinds: osteo, rheumatoid, gouty)
  • always take with food or after meals
  • IV formulation used for treatment of Patent ductus arteriosis
  • 25 - 50 mg bid-tid
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9
Q

Feldene

A
  • piroxicam
  • just for arthrtitis
  • half life = 50 hours
  • 20 mg/day
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10
Q

Mobic

A
  • meloxicam
  • just for arthrtitis (osteoarthritis)
  • affects Cox2 more than Cox1 = less GI problems
  • 7.5 - 15 mg daily
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11
Q

Voltaren

A
  • diclofenac sodium
  • arthritis (strong and potent)
  • strong: can cause some GI problems
  • Ophthalmic formulation: post-op opthalmic inflammation
  • Oral: 50mg tid-qid; XR: 100-200mg/d
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12
Q

Clinoril

A
  • sulindac
  • just for arthritis
  • prodrug (problem for pts with liver disease)
  • 150 mg bid
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13
Q

Lodine/XL

A
  • etodolac
  • affects Cox2 more than Cox1 = less GI problems
  • IR = acute pain; XL = chronic pain
  • 300-400mg bid or tid
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14
Q

If you can’t take celebrex, which medication would you be one?

A
  • Lodine

- Mobic

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15
Q

Toradol

A
  • ketorolac
  • potent
  • Moderately severe acute pain
  • not to use more than 5 days -> risks of GI bleed
  • 10 mg tab every 4-6 h
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16
Q

Relafen

A
  • nabumetone
  • arthritis
  • prodrug
  • easier on the stomach; take with food
  • 500 - 2000 mg in one or 2 doses
17
Q

Celebrex

A
  • celecoxib
  • COX-2 inhibitor
  • OA, RA
  • Contraindicated in patients with sulfonamide allergy
  • OA: 100 mg bid or 200 mg daily
  • RA: 100 - 200 mg bid
18
Q

Arthrotec

A
  • Diclofenac Sodium and Misoprostol
  • NSAID / Prostaglandin E1 analog
  • Treatment of arthritis in patients at high risk of NSAID-induced ulcers
  • Black box: Contraindicated in pregnant women
  • 50 mg/200 mcg tid