Test 1 Drug 45-92 Classifications Flashcards
1
Q
Classifications
A
- cholinergic / muscarinic agonist
- anticholinergic / antimuscarinic
- beta-1 agonist
- beta-2 agonist
- beta blockers
- Ach inhibitor
- alpha-1 agonist
- alpha-2 agonist
- alpha-1 antagonist
- neurotransmitter re-uptake inhibitors
2
Q
cholinergic / muscarinic agonist effects
A
- stimulates parasymptathetic system (rest and digest)
- miosis
- increased salivation and sweating
- increased vagal tone
- decrease HR
- bronchoconstriction
- nausea, anorexia
- increased motility
3
Q
What does the vagal nerve do?
A
takes Ach to heart and slows it down
4
Q
SLUDGEM
A
S - salivation L - lacrimation U - urination D - defecation G - gastrointestinal upset E - emesis (vomiting) M - miosis/muscle spasm
5
Q
DUMBELSS
A
D - diarrhea/defecation U - urination M - miosis/muscle weakness B - bronchorrhea B - bradycardia E - emesis L - lacrimation S - salivation S - sweating
6
Q
anticholinergic / antimuscarinic effects
A
- stimulate sympathetic system
- confusion
- drowsiness
- forgetfullness
- dry mouth
- mydriasis
- decreased vagal tone
- increased HR
- bronchodilation
- constipation
- increased bladder sphincter tone
- dry skin
- decreased sweating -> inability to regulate body temperature
7
Q
consequences and treatment of dry mouth
A
- consequences: difficulty talking
- treatment: candy, artificial saliva, Saligen
8
Q
alpha-1 agonist effects
A
- insomnia
- for topical products: rebound vasodilation of ocular and nasal vessels with prolonged use
- mydriasis
- constriction of arterioles -> increase HR and BP
- increased sphincter tone -> decreased voidsing
9
Q
alpha-2 agonist effects
A
- decrease sympathetic outflow
- decrease how much EPI and NE your body releases
- drowsiness
- dizziness
- fatigue
- dry mouth
- orthostatic hypotension
- decreased motility -> constipation
- decreased secretions
10
Q
beta-2 agonist effects
A
- insomnia
- nervousness
- increased HR and BP
- bronchodilation
- nausea
- increased blood glucose
- relaxation of uterine smooth muscle
- tremor
- increased K+ uptake
11
Q
neurotransmitter re-uptake inhibitor classes
A
- tricyclic anti-depressants
- non-selective MAO inhibitor
12
Q
alpha-1 antagonist effects
A
- dizziness
- headache
- 1st dose syncope
- dilation of arteriole -> hypotension
- reflex tachycardia
- peripheral edema
- decreased tone of bladder sphincter and prostate
13
Q
beta blocker effects
A
- do NOT use in pts with restrictive airway conditions (COPD, asthma, etc)
- dizziness
- drowsiness
- fatigue
- decreased HR
- orthostatic hypotension
- decreased renin secretion
