Test 1 Anticholinergic / antimuscarinic

Question 1

drugs

Answer 1

• Spiriva
• Transderm-Scop
• Tudorza
• Combivent
• Bentyl
• Duoneb
• Detrol
• Isopto Atropine
• Levsin, Levbid
• Cogentin
• Atrovent
• Ditropan

Question 2

Isopto Atropine

Answer 2

• atropine
• muscarinic antagonist
• induce mydriasis and cycloplegia
• wear sunglasses

Question 3

Transderm-Scop

Answer 3

• scopolamine
• muscarinic antagonist
• used for motion sickness
• apply 4 hours prior to desired time of effect
• replace every 72 hours
• adverse effects: anticholinergic effects on body

Question 4

Cogentin

Answer 4

• benztropine
• muscarinic antagonist
• used in Parkinsons
• decreased ability to sweat: use caution in hot weather
• 0.5 - 2 mg daily

Question 5

Bentyl

Answer 5

• dicyclomine
• anticholinergic
• used in IBS (relaxes smooth muscle in GI)
• administer 30 min before meal to decrease chances of muscle spasm
• adverse effects: anticholinergic effects
• 20-40 mg tid - qid

Question 6

Levsin, Levbid

Answer 6

• hyoscyamine sulfate
• anticholinergic
• used in IBS
• if used in emergency room, used for spastic colon
• oral tablets: take on empty stomach before meal
• also comes in SL and SR
• Levsin 0.125mg tabs: 0.125-0.25 mg q4h prn
• Levbid: 1 - 2 capsules q12h

Question 7

Ditropan

Answer 7

• oxybutynin
• urinary antispasmodic
• treat overactive bladder
• will have systemic side effects
• 5 mg tid or 5 mg XL daily

Question 8

Detrol, Detrol LA

Answer 8

• tolterodine
• urinary antispasmodic
• competitive muscarinic receptor antagonist
• treats overactive bladder
• 2 mg tab bid or 4 mg LA cap daily

Question 9

Atrovent

Answer 9

• ipratropium
• anticholinergic
• used for COPD; bronchial smooth muscle relaxation
• 2 puffs (or 1 vial of nebulizer solution) tid-qid

Question 10

Combivent, Duoneb

Answer 10

• ipratropium and albuterol
• anticholinergic + beta 2 agonist
• used for COPD; treats bronchospasm where a bronchodilator is not enough
• set schedule; NOT PRN
• no systemic effect
• adverse effect: dry mouth
• 2 puffs qid
• one vial via nebulizer qid

Question 11

Spiriva

Answer 11

• tiotropium
• anticholinergic
• COPD
• use i puff QD
• rinse mouth and spit (b/c of dry mouth)

Question 12

Tudorza

Answer 12

• alidinium bromide
• anticholinergic
• COPD
• use i puff Q12H