Test 2: Lecture 16 heart 2 Flashcards
how does foramen ovale close
increased pressure in left atrium from increased blood causes the thin septum primum to push against the thicker septum secundum and close the foramen ovale
ductus arteriosus closes ___
reflexively
ductus venous, umbilical vein and umbilical artery ___ to prevent blood loss
constrict
Fetal ductus arteriosus:
•Allows blood to bypass the lungs, which are not inflating or exchanging oxygen
•Blood goes from pulmonary artery through ductus to the aorta (R to L flow)
•Inflation of lungs and increase in the oxygen tension of blood causes smooth muscle in the ___ to constrict, closing the lumen
ductus arteriosus
What is the disorder if the smooth muscle ring is not complete and ductus arteriosus remains open ?
patent ductus arteriosus
Patent ductus arteriosus is bad because
pressure is much higher in aorta and will force blood from the aorta into the pulmonary artery- lungs get increased blood, body gets less blood
high velocity= turbulent = murmur
this is the opposite direction of blood flow in the fetus when blood went from pulmonary artery through the ductus arteriosus into the aorta to skip the lungs
What does a heart with PDA sound like
continuous heart murmur
blood constantly leaving the aorta into the pulmonary arteries which leads to overload of pulmonary capillaries→ pulmonary edema → heart failure
PDA circulation
•PDA→ Pulmonary artery → pulmonary capillaries → pulmonary veins → left atrium and ventricle → aorta
PDA leads to
pulmonary edema and heart failure
how to diagnosis PDA
hear murmur on auscultation
echocardiogram (transesophageal)
angiography
radiograph
How to treat PDA
surgical ligation around the PDA at open chest surgery
non invasive: devise occlusion of the PDA
pulmonary valve
•Valve that connects pulmonary artery and right ventricle:
semilunar valve
aortic valve
Valve that connects aorta and left ventricle
semilunar valve
when the opening of a valve is narrowed or formed incorrectly it leads to ___
valve stenosis
pulmonic valve stenosis
Increase in heart muscle mass - apoptosis did not work correctly
Decreased blood flow- valve doesn’t open all the way not as much blood gets through causes murmur
Arrhythmias (abnormal heart rhythms)
common in small breed dogs
Symptoms:
Congestive heart failure
Exercise intolerance
Fainting
Treatment:
balloon is used to break leaflets apart
Ventricular ___ divides the ventricle in left and right halves
septum
when there is a whole in the ventricular septum called a ___, blood will flow from ___
ventricular septum defect (VSD)
high pressure (left)
to low pressure (right)
this will cause build up in the lungs→ congestive heart failure
Bulbus cordis helps form dorsal portion of the ___, continues into ___, which forms spiral structure of the aorta and pulmonary artery.
spiral septum
truncus arteriosus
Division of the ___ and placement of the bulbar cordis/septum on top of the ventricular septum occurs at same time
truncus arteriosus
Bulbar cordis/septum needs to line up correctly with the interventricular septum to place the ___ over the right ventricle and ___ over the left ventricle
pulmonary artery
aorta
tetralogy of fallot
•4 defects resulting from failure of conotruncal(spiral) septum to align with the the ventricular septum
Failure of ventricular septum to fully close: ventricular septal defect (VSD)
Narrowed right-sided opening from the right ventricle leading to pulmonic valve stenosis
Rightward deviation of the left sided opening from the left ventricle leading to rightward positioning of the aorta
Right heart enlargement secondary to pulmonic valve stenosis
what does tetralogy of fallot cause
blood to flow Right to left
skips the lungs and deoxygenated blood is circulated into the body this leads to cyanosis
lethargy, exercise intolerance, RBC increases in number
what breed is common to get tetralogy of fallot
keeshond dog
persistent right aortic arch
PRAA
right aortic arch is supposed to regress, when it doesn’t aorta will form on that side, and left aortic arch will become ligament
problem happens because the RAA traps the esophagus and constricts the esophagus leading to regurgitation (food can’t fit past will come back up) will create a megaesophagus
Treatment cut Left aortic arch remnant
___ is the most common congenital heart disease of small breed dogs.
PDA patent ductus arteriosus
pulmonary to aorta pathway that skips lungs in fetus remains open and leads blood to go from aorta into the pulmonary, which overworks the lungs and leads to pulmonary edema and heart failure
treatment: coil placed that will form clot and close off ductus arteriosus
___, which uses sound waves (ultrasound), is the most common way to diagnose and examine PDA cases.
Echocardiography
A narrowed or fused valve is termed ___, and ___ of the pulmonary valve (PV), which lies between the right ventricle and pulmonary artery is the second most common congenital defect of dogs.
stenotic
stenosis
Hole in the ventricular septum is termed a ___
ventricular septal defect (VSD).